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Supercritical Fluid Chromatography - Quiz
  • 1. Which of the following is commonly used as the mobile phase in SFC?
A) Acetone
B) Water
C) Methanol
D) Carbon dioxide
  • 2. What state is the mobile phase in SFC?
A) Supercritical
B) Gas
C) Solid
D) Liquid
  • 3. What is the mechanism of separation in SFC based on?
A) Differences in boiling point
B) Differences in molecular weight
C) Differences in solubility in the mobile phase
D) Differences in conductivity
  • 4. What is the purpose of using a back pressure regulator in SFC?
A) Enhance detector sensitivity
B) Avoid solvent contamination
C) Increase column temperature
D) Maintain supercritical conditions
  • 5. What advantage does SFC offer over traditional HPLC?
A) Higher resolution
B) Faster separation
C) Lower equipment cost
D) Limited application range
  • 6. What role does co-solvent play in SFC separations?
A) Reduces detector interference
B) Enhances analyte solubility
C) Stabilizes column efficiency
D) Improves stationary phase selectivity
  • 7. Which term describes the region where the mobile phase in SFC exhibits properties of both a liquid and a gas?
A) Critical point
B) Supercritical zone
C) Near-critical region
D) Transition zone
  • 8. At supercritical conditions, the density of carbon dioxide is similar to that of which phase?
A) Aqueous
B) Liquid
C) Gas
D) Solid
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