Molecular virology
  • 1. Molecular virology is a branch of virology that focuses on studying the genetic material, replication, and interactions of viruses at the molecular level. This field delves into the structure and function of viral components such as nucleic acids, proteins, and membranes, and their intricate roles in viral infection and pathogenesis. By investigating the molecular mechanisms underlying viral replication, host-virus interactions, immune responses, and antiviral strategies, molecular virologists contribute significantly to our understanding of viral diseases and the development of novel therapeutics and vaccines.

    What is a viral capsid?
A) Lipid membrane surrounding virus
B) Protein shell that encloses viral genome
C) Energy-producing organelle
D) Enzyme that breaks down host cell DNA
  • 2. What is a bacteriophage?
A) Virus that infects plants
B) Virus that infects bacteria
C) Virus that infects animals
D) Virus that infects fungi
  • 3. Which enzyme is crucial for retrovirus replication?
A) Reverse transcriptase
B) Ligase
C) DNA polymerase
D) RNA polymerase
  • 4. What is the function of a viral envelope?
A) Facilitates entry into host cell
B) Protects viral genome
C) Produces energy
D) Regulates gene expression
  • 5. What is antigenic drift in viruses?
A) No change in viral structure
B) Minor changes in viral proteins over time
C) Mutation in viral replication enzyme
D) Rapid and massive change in viral genome
  • 6. How do vaccines protect against viral infections?
A) By directly destroying viruses
B) By triggering the immune system to produce antibodies
C) By inhibiting viral replication
D) By increasing viral mutation rate
  • 7. What is the role of a viroporin in virus replication?
A) Packages viral genome into new virus particles
B) Forms channels in host cell membrane for viral entry and release
C) Promotes immune response against virus
D) Helps virus replicate its genome
  • 8. Which virus is responsible for causing AIDS?
A) Herpes Simplex Virus
B) Rotavirus
C) HIV (Human Immunodeficiency Virus)
D) Influenza Virus
  • 9. How do virophages differ from traditional viruses?
A) Replicate outside of host cell
B) Contain both DNA and RNA genomes
C) Are larger in size
D) Infect other viruses rather than host cells
  • 10. Which cellular organelle is often exploited by viruses for replication and assembly of viral particles?
A) Nucleus
B) Golgi apparatus
C) Endoplasmic reticulum
D) Mitochondria
  • 11. Which viral family does the human immunodeficiency virus (HIV) belong to?
A) Orthomyxoviridae
B) Retroviridae
C) Picornaviridae
D) Herpesviridae
  • 12. What is the viral protein that helps to initiate the synthesis of viral RNA from the viral DNA template called?
A) DNA polymerase
B) RNA polymerase
C) Primase
D) Helicase
  • 13. What is the name given to a virus particle outside a host cell that consists of a nucleic acid core surrounded by a protein coat?
A) Virion
B) Capsid
C) Envelope
D) Spike
  • 14. What is the term for a virus that infects bacteria?
A) Phage virus
B) Bacterial virus
C) Prokaryophage
D) Bacteriophage
  • 15. What is the importance of viral receptors in host specificity?
A) Produces energy for virus
B) Regulates viral protein expression
C) Determines which host cells a virus can infect
D) Aids in viral replication
  • 16. What is the term for the process by which viruses acquire new genetic material from different sources?
A) Mutation
B) Recombination
C) Translation
D) Replication
  • 17. What do helical symmetries refer to in viruses?
A) Response of host cells to viral infection
B) Mode of viral transmission
C) Structure of viral capsid proteins arranged in a helix
D) Type of viral envelope
  • 18. Which viral disease has been eradicated through a successful vaccination campaign?
A) Ebola
B) Smallpox
C) Influenza
D) Polio
  • 19. What is the virus that causes COVID-19 classified as?
A) Paramyxovirus
B) Rhabdovirus
C) Filovirus
D) Coronavirus
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