Kidney transplantation - Quiz
  • 1. In what year did Canadian hockey player David Ayres receive a kidney transplant?
A) 2010
B) 1997
C) 2004
D) 2005
  • 2. Which spouse of a German president received a kidney transplant in 2010?
A) Sarah Hyland
B) Elke Büdenbender
C) Natalie Cole
D) Selena Gomez
  • 3. How many kidney transplants did American actor Gary Coleman receive?
A) Two
B) One
C) Three
D) Four
  • 4. In what year did English footballer Andy Cole receive his kidney transplant?
A) 2017
B) 2012
C) 2015
D) 2007
  • 5. How many years did American singer Natalie Cole survive after her 2009 kidney transplant?
A) 11 years
B) 6 years
C) 4 years
D) 8 years
  • 6. In what year did English actress Lucy Davis receive her kidney transplant?
A) 1990
B) 1997
C) 2004
D) 2000
  • 7. Who was the American basketball player that received a kidney transplant in 1999?
A) Sean Elliott
B) Alonzo Mourning
C) Ron Springs
D) Kenny Easley
  • 8. In what year did American actress Sarah Hyland receive her kidney transplant?
A) 2017
B) 2012
C) 2005
D) 2007
  • 9. Which American basketball player received a kidney transplant in 2003?
A) Sean Elliott
B) Ron Springs
C) Kenny Easley
D) Alonzo Mourning
  • 10. How long did Australian activist Charles Perkins survive after his 1972 kidney transplant?
A) 28 years
B) 5 years
C) 8 years
D) 14 years
  • 11. How long did Japanese wrestler Tomomi "Jumbo" Tsuruta survive after his 2000 transplant?
A) 4 years
B) 1 month
C) 11 years
D) 5 years
  • 12. In what year did American comedian George Lopez receive his kidney transplant?
A) 2003
B) 2010
C) 2005
D) 2007
  • 13. Which American poker player received a kidney transplant in 2004?
A) Jennifer Harman
B) Tracy Morgan
C) George Lopez
D) Steven Cojocaru
  • 14. In what year did American comedian Tracy Morgan receive his kidney transplant?
A) 2017
B) 2010
C) 2005
D) 2007
  • 15. What are the two primary requirements for donor-recipient compatibility in kidney transplantation?
A) ABO blood group and HLA compatibility
B) HLA matching and blood pressure
C) Age and organ size
D) Blood group and gender
  • 16. What is the alternative term for 'kidney exchange'?
A) Kidney paired donation
B) Organ recycling
C) Sequential matching
D) HLA-swapping
  • 17. What therapy was approved by the FDA in 2004 to reduce the need for ABO compatibility?
A) Plasmapheresis
B) Immunosuppressive steroid therapy
C) Cedars-Sinai High Dose IVIG
D) Lich-Gregoir therapy
  • 18. How is the level of sensitization to donor HLA antigens determined?
A) Panel reactive antibody test
B) ABO blood typing
C) Urinalysis
D) Genetic chromosome analysis
  • 19. In the United States, what percentage of deceased donor kidney transplants have no HLA mismatch?
A) Up to 17%
B) Up to 5%
C) Up to 33%
D) Up to 50%
  • 20. Why are the recipient's original kidneys usually left in place during a transplant?
A) Removal increases the risk of infection
B) They are difficult to surgically reach
C) Removal increases surgical morbidity
D) They help with hormone regulation
  • 21. Where is the donor kidney typically placed in the recipient?
A) Right-sided iliac fossa
B) Upper abdominal cavity
C) The original renal bed
D) The left-sided lumbar region
  • 22. To which vessel is the donor renal artery typically connected in the recipient?
A) Abdominal aorta
B) External iliac artery
C) Inferior vena cava
D) Internal iliac artery
  • 23. To which vessel is the donor renal vein typically connected in the recipient?
A) Inferior vena cava
B) Common iliac vein
C) External iliac vein
D) Renal vein
  • 24. What technique avoids the need for ureteral stenting during kidney transplantation?
A) Ciancio-Lich method
B) Iliac anastomosis protocol
C) Campbell's technique
D) Modified Lich-Gregoir technique
  • 25. Which textbook recommends the right side for transplantation if there is doubt about pelvic space?
A) Smith's Urology
B) The Journal of Transplantation
C) Campbell's Urology
D) Glen's Urological Surgery
  • 26. Why does Campbell's Urology recommend placing the kidney on the contralateral side?
A) To ensure the renal pelvis and ureter are anterior
B) To reduce blood supply distance
C) To improve postoperative pain management
D) To keep the vessels more horizontal
  • 27. According to Smith's Urology, why is the right side of the pelvis often preferred for anastomoses?
A) There is more room in the pelvis
B) It is easier to reach the bladder
C) Vessels are more horizontal
D) It reduces the risk of rejection
  • 28. What historical experimental protocol was used in the 1980s for ABO-incompatible transplants?
A) Lich-Gregoir stenting
B) Kidney paired donation
C) IVIG and gene therapy
D) Plasmapheresis and increased immunosuppression
  • 29. Which country in the UK was the first to enable an opt-out organ donation register?
A) Scotland
B) Wales
C) England
D) Northern Ireland
  • 30. What is the term used for the legislation where citizens are considered donors unless they opt out?
A) Mandatory donation
B) Active enrollment
C) Voluntary opt-in
D) Deemed consent
  • 31. In what year was the Human Transplantation (Wales) Act 2013 implemented?
A) 2022
B) 2015
C) 2013
D) 2020
  • 32. Which medication approved in 2020 helped increase the number of available organ donors?
A) Antibiotic
B) Epclusa
C) Hepatitis C vaccine
D) Immunosuppressant
  • 33. How does Epclusa increase the donor pool?
A) By preventing organ rejection
B) By curing Hepatitis C positive individuals
C) By extending organ shelf-life
D) By promoting opt-in registration
  • 34. Where was the 2022 research on pig kidney transplants conducted?
A) Oxford University
B) Johns Hopkins University
C) University of Alabama, Birmingham
D) Massachusetts General Hospital
  • 35. In which journal was the 2022 pig kidney transplant study published?
A) The Lancet
B) New England Journal of Medicine
C) Nature Medicine
D) American Journal of Transplantation
  • 36. What was the medical status of the human recipient in the 2022 pig kidney transplant study?
A) End-stage renal failure
B) Acute kidney injury
C) Brain-dead
D) Healthy volunteer
  • 37. Where did the pig kidneys used in the 2022 study originate?
A) A pathogen-free facility
B) A wild boar habitat
C) A veterinary clinic
D) A local farm
  • 38. When did surgeons at Massachusetts General Hospital transplant a pig kidney into a 62-year-old man?
A) December 2015
B) March 2024
C) January 2022
D) December 2020
  • 39. What happened to the recipient's native kidneys in the 2022 study?
A) They were temporarily bypassed
B) They were repaired
C) They were left in place
D) They were removed
  • 40. What is the traditional incision size for a donor procedure?
A) 1–3 inches
B) 12–15 inches
C) 4–7 inches
D) 8–10 inches
  • 41. After how many cases does a surgeon's operative time and complications significantly decrease?
A) 100 cases
B) 300 cases
C) 50 cases
D) 150 cases
  • 42. Which type of kidney graft has higher long-term success rates?
A) Live donor grafts
B) Synthetic grafts
C) Deceased donor grafts
D) Robotic-assisted grafts
  • 43. Where was the first all-robotic kidney transplant performed in 2009?
A) Mayo Clinic
B) Cleveland Clinic
C) Saint Barnabas Medical Center
D) Johns Hopkins Hospital
  • 44. Where is Saint Barnabas Medical Center located?
A) Baltimore, Maryland
B) New York, New York
C) Boston, Massachusetts
D) Livingston, New Jersey
  • 45. How many robotic-assisted transplants were performed by the Saint Barnabas team in the six months following January 2009?
A) Five
B) Twelve
C) Eight
D) Ten
  • 46. Where was the 2009 vaginal kidney donation performed?
A) Harvard Medical School
B) Johns Hopkins Hospital
C) University of Maryland Medical Center
D) Saint Barnabas Medical Center
  • 47. What surgical method was used for the vaginal kidney extraction?
A) Robotic-assisted traditional laparoscopy
B) Open surgery
C) Laser-guided microsurgery
D) Natural orifice transluminal endoscopic surgery
  • 48. What is the entry point for single port laparoscopy?
A) The navel
B) The lower back
C) The vagina
D) The side of the abdomen
  • 49. What potential effect do advances in surgical techniques have on kidney donation?
A) Boost donor numbers
B) Increase surgical costs
C) Decrease graft success rates
D) Require longer recovery times
  • 50. What is the primary goal of the donor screening process?
A) Reducing the cost of surgical procedures
B) Increasing the number of available hospital beds
C) Ensuring good long-term outcomes
D) Maximizing the number of transplants performed
  • 51. What is a major risk of a prolonged donor evaluation process?
A) The hospital loses surgical funding
B) The donor's insurance expires
C) The recipient becomes too ill for transplant
D) The donor changes their mind
  • 52. Why is it important to check for diseases that could be transmitted to the recipient?
A) The recipient is usually immunosuppressed
B) The donor needs to be cured first
C) It is a legal requirement for all surgeries
D) It prevents the donor from getting sick
  • 53. What medical aspect of the donor's kidney is evaluated?
A) Anatomy
B) Color
C) Blood type alone
D) Weight
  • 54. Which condition is a common exclusion criterion for kidney donation?
A) History of broken bones
B) Minor allergies
C) Diabetes
D) Corrected vision
  • 55. What is evaluated regarding kidney function during medical screening?
A) Heart rate variability
B) Blood glucose levels
C) Proteinuria
D) Lung capacity
  • 56. What does psychosocial screening investigate regarding family involvement?
A) Financial contribution
B) Genetic compatibility
C) Employment status
D) Coercion
  • 57. Which of these is a listed exclusion criterion for potential donors?
A) Mild anxiety
B) Controlled asthma
C) A history of appendicitis
D) Severe obesity
  • 58. Which of the following is considered an exclusion criterion?
A) Occasional headaches
B) High cholesterol
C) Controlled mild hypertension
D) Uncontrolled hypertension
  • 59. What might cause the screening process to take longer than a few months?
A) The need for additional tests
B) The donor's geographic location
C) Changes in federal law
D) A lack of hospital staff
  • 60. What percentage of kidney transplants in the United States are attributed to diabetes?
A) Approximately 25%
B) Approximately 5%
C) Approximately 10%
D) Approximately 50%
  • 61. What is the most common cause of end-stage renal disease overall?
A) Genetic disorders
B) Infection
C) Lupus
D) Idiopathic
  • 62. Which of the following is listed as a contraindication for a recipient?
A) Controlled hypertension
B) Hepatic disease
C) Stable asthma
D) Mild depression
  • 63. What does a candidate need to demonstrate for transplant survival?
A) High fitness levels
B) Medication compliance
C) Family support
D) Ability to pay
  • 64. Which behavior is specifically mentioned as putting a patient at higher risk for surgical complications?
A) Low protein diet
B) Increased water intake
C) Regular physical exercise
D) Tobacco use
  • 65. Who was awarded the Nobel Prize in 1990 for his work in kidney transplantation?
A) Thomas Starzl
B) Hartwell Harrison
C) Richard Lawler
D) Joseph Murray
  • 66. Where is the new kidney typically placed during transplant surgery?
A) In the upper back
B) Replacing the native kidney in its original position
C) In the chest cavity
D) In the lower abdomen
  • 67. Who attempted the first human kidney transplant in 1933?
A) Simon Flexner
B) Richard Lawler
C) Yuriy Voronyi
D) Jean Hamburger
  • 68. What percentage of kidney transplants worldwide in 2018 came from living donors?
A) 36%
B) 10%
C) 50%
D) 25%
  • 69. What is the basis for most immunosuppressive regimens in kidney transplant patients?
A) Prednisolone
B) Tacrolimus
C) Ciclosporin
D) Azathioprine
  • 70. What is a common side effect of long-term high-dose prednisolone use?
A) Improved muscle strength
B) Hyperglycemia relief
C) Osteoporosis
D) Increased skin elasticity
  • 71. What percentage of donated kidneys in the United States came from living donors in 2006?
A) 50%
B) 47%
C) 3%
D) 33%
  • 72. Between whom were the first successful living donor kidney transplants performed in the 1950s?
A) Spouses
B) Siblings who were not twins
C) Strangers
D) Identical twins
  • 73. How many participants were involved in the world's longest kidney transplant chain record in 2014?
A) 70
B) 30
C) 60
D) 100
  • 74. According to the 2017 NEJM article, what should kidney donors limit to reduce long-term health risks?
A) Physical exercise
B) Protein intake
C) Water consumption
D) Vitamin supplements
  • 75. Who developed the concept of open-ended chains?
A) Chris Strouth
B) The National Kidney Registry
C) Michael Rees
D) The FDA
  • 76. Which organization was established by medical anthropologists to expose illegal organ-selling rings?
A) International Transplant Ethics Board
B) National Kidney Research Fund
C) Organs Watch
D) Global Organ Initiative
  • 77. What is a common complication risk for patients involved in the illegal organ trade?
A) Legal prosecution
B) Excessive organ cooling
C) Over-prescription of heparin
D) Poor infection control
  • 78. In how many countries is monetary compensation for organ donors in the form of reimbursement legal?
A) 10
B) 23
C) 100
D) 50
  • 79. Which substance is used to prevent coagulation during organ recovery from DCD donors?
A) NaCl-solution
B) HTK solution
C) Viaspan
D) Heparin
  • 80. Which of the following is an example of an organ storage solution mentioned in the text?
A) NaCl
B) Glucose
C) HTK
D) Heparin
  • 81. In what year was the first simultaneous pancreas-kidney transplant performed?
A) 1976
B) 1980
C) 1990
D) 1966
  • 82. What is the abbreviation for a pancreas-after-kidney transplant?
A) PAK
B) KPT
C) SKP
D) PKT
  • 83. How long does a typical kidney transplant surgery take?
A) 3 to 5 days
B) 4 to 10 days
C) 7 to 15 days
D) About three hours
  • 84. How long do living donor kidneys typically take to reach normal functioning levels?
A) 3–5 days
B) 1–2 days
C) 7–15 days
D) 4–10 days
  • 85. What medication is used if complications arise to help produce urine?
A) Prednisolone
B) Diuretics
C) Ciclosporin
D) Tacrolimus
  • 86. What is a known side effect of both ciclosporin and tacrolimus?
A) Nephrotoxicity
B) Ureter rejection
C) Increased insulin production
D) Liver failure
  • 87. When was ciclosporin discovered to be a breakthrough immunosuppressant?
A) The 1980s
B) The 1970s
C) The 1990s
D) The 1960s
  • 88. Which imaging modality is used periodically to assess for transplant rejection?
A) CT scan
B) PET scan
C) MRI
D) Ultrasound
  • 89. What is the normal value for the resistive index (RI) in a transplanted kidney?
A) 0.70
B) 0.50
C) 0.80
D) 0.60
  • 90. Which food product should be avoided by kidney transplant recipients due to drug interactions?
A) Grapefruit
B) Spinach
C) Apples
D) Carrots
  • 91. Which medication levels can be increased by consuming grapefruit, pomegranate, or green tea?
A) Tacrolimus
B) Aspirin
C) Insulin
D) Metformin
  • 92. Which side effect is specifically associated with the medication ciclosporin?
A) Hair loss
B) Hirsutism
C) Tinnitus
D) Blindness
  • 93. What is the most common cause of transplant failure one year or greater after transplantation?
A) Glomerulonephritis
B) Acute rejection
C) Vascular thrombosis
D) Chronic rejection
  • 94. Infections in kidney transplant recipients most commonly occur in which area?
A) Urinary tract
B) Respiratory tract
C) Mucocutaneous areas
D) Central nervous system
  • 95. What is the most common infective agent in kidney transplant recipients?
A) Bacterial
B) Fungal
C) Viral
D) Protozoan
  • 96. Which viral illness is the most common among post-transplant viral infections?
A) Herpes simplex
B) Herpes zoster
C) Human cytomegalovirus
D) Influenza
  • 97. What accounts for 50% of patient deaths from infection post-transplant?
A) Meningitis
B) Sepsis
C) Colitis
D) Pneumonias
  • 98. What is the mortality rate for COVID-19 in kidney transplant recipients?
A) 13-32%
B) 40-50%
C) 1-5%
D) 5-10%
  • 99. Which virus is increasingly recognized as a transplant risk factor that may lead to failure?
A) HPV
B) BK virus
C) Ebola
D) Hepatitis C
  • 100. Which of the following professional athletes is mentioned as having a kidney transplant?
A) Jonah Lomu
B) David Beckham
C) Michael Jordan
D) Usain Bolt
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