Chirality in chemistry

1. What does it mean for a molecule to be chiral?

A) It has no stereocenters.
B) It has no optical rotation.
C) It has a linear structure.
D) It cannot be superimposed on its mirror image.

2. What is a stereocenter?

A) An atom that is bonded to four different groups.
B) An atom that is bonded to four identical groups.
C) An atom that is bonded to three different groups.
D) An atom that is bonded to two groups.

3. How many stereoisomers can a chiral molecule with one stereocenter have?

A) 3
B) 4
C) 1
D) 2

4. Which type of light is used in optical rotation experiments?

A) Ultraviolet light.
B) Plane-polarized light.
C) Visible light.
D) Infrared light.

5. What is an optically active compound?

A) A compound with no stereocenters.
B) A compound with high molecular weight.
C) A compound that absorbs light.
D) A compound that rotates the plane of polarized light.

6. What is a racemic mixture?

A) A mixture of structurally different molecules.
B) A mixture of meso compounds.
C) A mixture of diastereomers.
D) A 50:50 mixture of two enantiomers.

7. Why are enantiomers important in drug development?

A) They are easier to synthesize.
B) They have no medicinal value.
C) They can have different biological effects.
D) They have the same properties in the body.

8. How does chirality affect the physical properties of a molecule?

A) Diastereomers have identical boiling points.
B) Racemic mixtures have higher melting points than pure enantiomers.
C) Chiral molecules are always more soluble than achiral molecules.
D) Enantiomers have identical physical properties except for optical activity.

9. How can chirality be determined experimentally?

A) By measuring optical activity with a polarimeter.
B) By checking the molecular weight of a compound.
C) By analyzing the color of the substance.
D) By counting the number of carbons in a molecule.

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