Chirality in chemistry

1. What does it mean for a molecule to be chiral?

A) It has no optical rotation.
B) It cannot be superimposed on its mirror image.
C) It has a linear structure.
D) It has no stereocenters.

2. What is a stereocenter?

A) An atom that is bonded to four different groups.
B) An atom that is bonded to three different groups.
C) An atom that is bonded to two groups.
D) An atom that is bonded to four identical groups.

3. How many stereoisomers can a chiral molecule with one stereocenter have?

A) 4
B) 1
C) 3
D) 2

4. What is a racemic mixture?

A) A 50:50 mixture of two enantiomers.
B) A mixture of diastereomers.
C) A mixture of meso compounds.
D) A mixture of structurally different molecules.

5. Why are enantiomers important in drug development?

A) They can have different biological effects.
B) They have the same properties in the body.
C) They are easier to synthesize.
D) They have no medicinal value.

6. How can chirality be determined experimentally?

A) By counting the number of carbons in a molecule.
B) By checking the molecular weight of a compound.
C) By measuring optical activity with a polarimeter.
D) By analyzing the color of the substance.

7. Which type of light is used in optical rotation experiments?

A) Ultraviolet light.
B) Plane-polarized light.
C) Infrared light.
D) Visible light.

8. What is an optically active compound?

A) A compound that rotates the plane of polarized light.
B) A compound with high molecular weight.
C) A compound that absorbs light.
D) A compound with no stereocenters.

9. How does chirality affect the physical properties of a molecule?

A) Enantiomers have identical physical properties except for optical activity.
B) Chiral molecules are always more soluble than achiral molecules.
C) Racemic mixtures have higher melting points than pure enantiomers.
D) Diastereomers have identical boiling points.

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