Chronic kidney disease - Quiz
  • 1. What is the primary driver of damage in obesity-related CKD?
A) High protein intake
B) Excessive water consumption
C) Visceral obesity
D) Low physical activity
  • 2. How much more likely are high calorie and high fructose beverages to make an individual develop CKD?
A) 50%
B) 30%
C) 60%
D) 75%
  • 3. Which of these is NOT listed as a weight management intervention for CKD?
A) Genetic counseling
B) Surgical interventions
C) Pharmacological interventions
D) Dietary changes
  • 4. What is the effect of reduced salt intake on albuminuria in CKD patients?
A) It has no effect
B) It fluctuates unpredictably
C) It may help lower it
D) It increases it
  • 5. What symptom may be associated with low blood pressure due to salt restriction?
A) Fever
B) Blurred vision
C) Dizziness
D) Joint pain
  • 6. Does Omega-3 supplementation prevent vascular blockage in CKD patients?
A) Only in early stages
B) No
C) Yes
D) Only in dialysis patients
  • 7. What effect do oral protein-based supplements have on serum albumin levels in CKD?
A) They may increase them slightly
B) They have no effect
C) They stabilize them perfectly
D) They decrease them significantly
  • 8. What is the known impact of weight loss interventions on preventing cardiovascular events in CKD patients?
A) It definitely prevents stroke only
B) It is not known
C) It prevents all events
D) It increases the risk
  • 9. Which tool might improve dietary sodium intake and fluid management for CKD patients?
A) Complete fasting
B) EHealth interventions
C) Hospital isolation
D) Daily surgery
  • 10. What is the effect of salt restriction on extracellular fluid and oedema in CKD patients?
A) The effect is unknown
B) It eliminates them entirely
C) It increases them
D) It decreases them
  • 11. What physiological change is linked to potential benefits from protein supplementation in CKD?
A) Decreased bone density
B) Decreased blood volume
C) Increased insulin resistance
D) Increased mid-arm muscle circumference
  • 12. How should weight management interventions for CKD patients be approached?
A) Based solely on BMI
B) Standardized for all patients
C) Individualized based on assessment
D) Determined by age alone
  • 13. For how long must a GFR be below 60 mL/min/1.73 m2 to be defined as chronic kidney disease?
A) 3 months
B) 1 month
C) 1 year
D) 6 months
  • 14. What urine albumin/creatinine ratio (ACR) value is used to define kidney damage?
A) ≥ 60
B) ≥ 15
C) ≥ 30
D) ≥ 50
  • 15. What does the letter 'P' signify in British guidelines for chronic kidney disease?
A) Potentially reversible damage
B) Persistent filtration loss
C) Significant protein loss
D) Primary renal failure
  • 16. What is the GFR range for Stage 3A chronic kidney disease according to British guidelines?
A) 60–89 mL/min/1.73 m2
B) 30–44 mL/min/1.73 m2
C) 45–59 mL/min/1.73 m2
D) 15–29 mL/min/1.73 m2
  • 17. What is the GFR range for Stage 3B chronic kidney disease according to British guidelines?
A) 45–59 mL/min/1.73 m2
B) 30–44 mL/min/1.73 m2
C) 15–29 mL/min/1.73 m2
D) 60–89 mL/min/1.73 m2
  • 18. What characterizes Stage 4 chronic kidney disease?
A) Severe reduction in GFR (15–29 mL/min/1.73 m2)
B) Established kidney failure
C) Slightly diminished function
D) Normal GFR with albuminuria
  • 19. What is the GFR threshold for Stage 5 chronic kidney disease?
A) <60 mL/min/1.73 m2
B) <30 mL/min/1.73 m2
C) <45 mL/min/1.73 m2
D) <15 mL/min/1.73 m2
  • 20. Which term describes persons with CKD who do not yet require kidney replacement therapy?
A) Acute renal failure
B) End-stage renal replacement
C) NDD-CKD
D) ESKD
  • 21. What does ESKD stand for?
A) Early stage kidney dysfunction
B) Excessive sodium kidney disorder
C) End-stage kidney disease
D) Established syndrome kidney damage
  • 22. What are the two types of kidney replacement therapy mentioned in the text?
A) Medication or surgery
B) Dietary changes or dialysis
C) Dialysis or transplantation
D) Transplantation or dietary therapy
  • 23. Is a person with Stage 5 CKD who has not started replacement therapy considered NDD-CKD?
A) Only if GFR is > 20
B) Yes
C) No
D) Only if protein loss is absent
  • 24. Protein in the urine is an independent marker for which two conditions?
A) Stage 1 CKD and Stage 5 CKD
B) High blood pressure and diabetes
C) Worsening kidney function and cardiovascular disease
D) Dialysis dependence and organ failure
  • 25. Which of the following is a common early indicator of CKD before symptoms appear?
A) Confusion
B) Severe leg swelling
C) Vomiting
D) Proteinuria
  • 26. What is a primary diagnostic test used to measure kidney function?
A) ECG
B) Estimated glomerular filtration rate (eGFR)
C) Skin biopsy
D) Blood pressure check
  • 27. Which condition is a leading cause of chronic kidney disease?
A) Fractures
B) Skin infections
C) Asthma
D) Diabetes
  • 28. What is the term for the crystallization of urea on the skin?
A) Cachexia
B) Edema
C) Azotemia
D) Uremic frost
  • 29. Which electrolyte abnormality is associated with cardiac arrhythmias in CKD patients?
A) Hyperkalemia
B) Hypernatremia
C) Hyponatremia
D) Hypocalcemia
  • 30. Which medication type should be avoided in patients with CKD?
A) ARBs
B) NSAIDs
C) ACEIs
D) Loop diuretics
  • 31. What is a major complication of CKD relating to red blood cell production?
A) Insulin resistance
B) Metabolic acidosis
C) Hyperphosphatemia
D) Anemia
  • 32. What is the recommended dietary approach for patients with CKD?
A) Ultraprocessed foods
B) High animal-based protein diet
C) Plant-based foods
D) Low carbohydrate ketogenic diet
  • 33. What is the leading cause of death associated with CKD mentioned in the data?
A) Cardiovascular complications
B) Diabetes
C) High blood pressure
D) Glomerulonephritis
  • 34. What term is used for CKD when the cause is unknown?
A) Congenital
B) Obstructive
C) Ischemic
D) Idiopathic
  • 35. Which of the following is an example of small-vessel vascular disease?
A) Polycystic kidney disease
B) Benign prostatic hyperplasia
C) Bilateral kidney artery stenosis
D) Ischemic nephropathy
  • 36. Which condition is classified as a primary glomerular disease?
A) Focal segmental glomerulosclerosis
B) Lupus nephritis
C) Diabetic nephropathy
D) Ischemic nephropathy
  • 37. What is a known potential cause of obstructive nephropathy?
A) IgA nephropathy
B) Benign prostatic hyperplasia
C) Lithium treatment
D) Chronic lead exposure
  • 38. Which rare cause of obstructive nephropathy is mentioned in the text?
A) Lead
B) High temperatures
C) Pinworms
D) Lithium
  • 39. What is Mesoamerican nephropathy sometimes called?
A) Agricultural nephropathy
B) Obstructive nephropathy
C) Glomerular nephropathy
D) Ischemic nephropathy
  • 40. Which factor is suspected to cause Mesoamerican nephropathy?
A) Congenital genetic mutations
B) Heat stress
C) Bacterial infection
D) High protein diet
  • 41. After how many years of lithium treatment can chronic kidney disease occur?
A) 5-10 years
B) 20-30 years
C) 1-5 years
D) 10-20 years
  • 42. What percentage of people may develop CKD from long-term lithium treatment?
A) 1-5%
B) 0.1-0.5%
C) 10-20%
D) 5-10%
  • 43. How can kidney harm be mitigated during lithium treatment?
A) Dosing three times per day
B) Dosing once per day at night
C) Avoiding all intake of water
D) Increasing the dose as much as possible
  • 44. Which group is recommended to undergo screening for CKD?
A) Individuals with no family history of illness
B) Healthy adults with no risk factors
C) Those with hypertension
D) Children under the age of 10
  • 45. What is the recommended timing for collecting urine for the albumin-to-creatinine ratio (ACR)?
A) First-morning urine specimen
B) 24-hour urine collection
C) Urine collected immediately after exercise
D) Random urine sample in the evening
  • 46. What is the relationship between GFR and serum creatinine?
A) No correlation
B) Directly proportional
C) Exponential
D) Reciprocal
  • 47. Which radioactive element is used in MAG3 and DMSA scans?
A) Carbon-14
B) Uranium-235
C) Iodine-131
D) Technetium-99
  • 48. Which test is used to confirm blood flow and differential function between the two kidneys?
A) Serum creatinine measurement
B) Nuclear medicine MAG3 scan
C) Urine dipstick
D) Physical palpation
  • 49. What does the GFR measure?
A) The total number of nephrons
B) How efficiently the glomeruli work
C) The concentration of hormones in the blood
D) The size of the ureters
  • 50. Which drug class is recommended to slow CKD progression in adults with an eGFR ≥20 mL/min/1.73 m²?
A) Statins
B) ACEIs
C) Phosphate binders
D) SGLT2 inhibitors
  • 51. What is the recommended target hemoglobin level for patients with anemia in CKD?
A) 120–140 g/L
B) 100–120 g/L
C) 80–100 g/L
D) 140–160 g/L
  • 52. What should be administered prior to treatment with erythropoietin in CKD patients?
A) Oral calcium
B) Parenteral iron
C) Zinc supplements
D) Vitamin D supplements
  • 53. What is the recommended daily protein intake for metabolically stable adults with CKD stages G3–G5?
A) Approximately 0.8 g/kg
B) Exactly 0.4 g/kg
C) More than 1.3 g/kg
D) Greater than 2.0 g/kg
  • 54. Which medication is recommended for the treatment of vitamin D deficiency and metabolic bone disease in CKD?
A) Calcitriol
B) Statins
C) Erythropoietin
D) Dapagliflozin
  • 55. Which of the following is used to control elevated serum phosphate levels in advanced CKD?
A) Gadolinium
B) Zinc
C) Phosphate binders
D) ACEIs
  • 56. Which group of people is a very-low-protein diet NOT recommended for due to growth concerns?
A) Elderly patients
B) Children
C) Patients with high blood pressure
D) Patients with diabetes
  • 57. What is a potential safety risk associated with intravenous iron therapy in CKD patients?
A) Vitamin toxicity
B) Increased blood pressure
C) Reduced kidney function
D) Allergic reactions
  • 58. Which activity may help with sleep regulation and decrease fatigue in CKD patients?
A) Exercise
B) Drinking coffee
C) Reducing social interaction
D) Increasing nocturnal fluid intake
  • 59. What is the current scientific consensus on the effectiveness of treatments for sleep disorders in CKD?
A) Relaxation techniques are highly effective
B) Medication is guaranteed to cure sleep disorders
C) Exercise is the gold standard treatment
D) None of the options have been proven effective
  • 60. At what stage of CKD is referral to a nephrologist generally considered required?
A) Stage 4
B) Stage 1
C) Stage 2
D) Stage 5 only
  • 61. What is a surgical benefit of early nephrology referral for those opting for hemodialysis?
A) Placement of an arteriovenous fistula
B) Removal of the kidneys
C) Transplant of a liver
D) Cardiac bypass surgery
  • 62. What is the cardiovascular disease prevalence in the Medicare population with CKD over age 66?
A) 80%
B) 32%
C) 65%
D) 50%
  • 63. What is a common complication of CKD in children and adolescents?
A) Increased bone density
B) Growth failure
C) Cognitive decline
D) Early puberty
  • 64. Which treatment appears to be associated with improved survival compared to conventional hemodialysis?
A) Medication-only therapy
B) Occasional peritoneal dialysis
C) Low-flux hospital hemodialysis
D) High-intensity home hemodialysis
  • 65. How many people in the U.S. were estimated to have CKD between 2017 and 2020?
A) 13.9%
B) 25%
C) 10%
D) 8.8%
  • 66. What is the primary occupation of those affected by Mesoamerican nephropathy (MeN)?
A) Sugarcane labourers
B) Fishermen
C) Office workers
D) Coal miners
  • 67. Which ethnic group is specifically mentioned as having high hypertension-related ESKD risk?
A) Native Americans
B) Caucasians
C) African Americans
D) Inuit populations
  • 68. What therapy is often required for black patients because standard antihypertensive drugs are less effective?
A) Bicarbonate therapy
B) Antibiotic therapy
C) Dialysis-only therapy
D) Insulin therapy
  • 69. In 2013, how many deaths were attributed to CKD globally?
A) 409,000
B) 1.2 million
C) 956,000
D) 250,000
  • 70. What is the rank of CKDu as a cause of in-hospital mortality in Sri Lanka?
A) Tenth
B) Third
C) Eighth
D) First
  • 71. What percentage of ESKD cases in Caucasians are attributed to high blood pressure?
A) 50%
B) 10%
C) 19%
D) 37%
  • 72. Which UK organization represents kidney physicians and works with the National Service Framework?
A) The UK National Kidney Federation
B) The International Society of Nephrology
C) Kidney Care UK
D) The Renal Association
  • 73. Which dog breed is listed as having one of the highest rates of CKD?
A) Boxer
B) Finnish spitz
C) Swedish elkhound
D) Siberian husky
  • 74. Which dog breed is listed as having one of the lowest rates of CKD?
A) Boxer
B) Bernese mountain dog
C) Miniature schnauzer
D) Siberian husky
  • 75. What condition in cats with CKD can lead to anemia?
A) Increased urine volume
B) Weight loss
C) Acidosis
D) Hypertension
  • 76. Which organization represents nephrology professionals in the United States?
A) The American Association of Kidney Patients
B) The American Kidney Fund
C) The National Kidney Foundation
D) The Renal Physicians Association
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