FS_FCTOXI
  • 1. Which route of entry produces the fastest effect?
    Oral
    Dermal
    Inhalation
    Rectal
A) Rectal
B) Dermal
C) Inhalation
D) Inhalation
E) Oral
  • 2. Forensic toxicology is best defined as the study of:
A) Poisons in industrial work
B) Chemical reactions in the body
C) Drugs used in medicine
D) Toxic substances in relation to law
  • 3. Which professional is responsible for analyzing drugs and poisons for court purposes?
A) forensic Pathologist
B) Medical technologist
C) Forensic toxicologist
D) Chemist
  • 4. Which of the following is NOT a branch of forensic toxicology?
A) Postmortem toxicology
B) Clinical pharmacology
C) Forensic drug testing
D) Human performance toxicology
  • 5. Forensic toxicology is MOST applicable in which investigation?
A) Arson
B) Theft
C) Forgery
D) Poisoning
  • 6. A poison is a substance that
A) Is always fatal
B) Is synthetic
C) Produces harmful effects when introduced into the body
D) Is illegal
  • 7. Which is classified as a mineral poison?
A) Cocaine
B) Morphine
C) . Nicotine
D) Arsenic
  • 8. Carbon monoxide is classified as a:
A) Metallic poison
B) Solid poison
C) Volatile liquid
D) Gaseous poison
  • 9. Acute poisoning means exposure that is:
A) Long-term
B) Sudden and short-term
C) Repeated
D) Occupational
  • 10. Distribution refers to the:
A) Removal of drugs
B) Breakdown of drugs
C) Entry of drugs into blood
D) Movement of drugs in the body
  • 11. The BEST blood sample in postmortem toxicology is:
A) Femoral blood
B) Jugular blood
C) Pulmonary blood
D) . Cardiac blood
  • 12. Decomposition may cause toxicology results to be:
A) Faster
B) Unaffected
C) More accurate
D) Misleading
  • 13. Long-term drug use is best detected using:
A) Hair
B) Blood
C) Saliva
D) Urine
  • 14. Which specimen best reflects recent drug use?
A) Bone
B) Hair
C) Blood
D) Nails
  • 15. Forensic toxicology is MOST important in which crime?
A) Estafa
B) Kidnapping
C) Drug-related offenses
D) Cybercrime
  • 16. A toxicologist testifying in court is called a(n):
  • 17. A toxicologist testifying in court is called a(n):
A) Expert witness
B) Arsenic
C) Mercury
D) Cyanide
  • 18. Forensic toxicology is MOST concerned with:
A) Drug marketing
B) Medical treatment
C) Legal interpretation of poisons
D) . Chemical synthesis
  • 19. The ultimate goal of forensic toxicology is to:
A) Support justice through science
B) Examination of his testimony
C) Discover new drugs
  • 20. Most common sample for resent drugs or alcohol use
A) Semen
B) Hair
C) . Blood and Urine
D) Tissue
  • 21. The most common sample used for drug test
A) Urine
B) saliva
C) Hashis
  • 22. A condition whrein males have no spermatozoa at all in their seminal fluid
A) Aspermia
B) Anemia
C) Oligospermia
  • 23. Application of benzidine test it gives what color?
A) Yellow
B) Blue
C) White
  • 24. In what mode of administration paison by causing production of sweat
A) Inhalation
B) Injection
C) Oral
D) Anal
  • 25. Which evidence offers strongest resistance to decomposition
A) Semen
B) Hair
C) Urine
D) Blood
  • 26. A condition in which the supply of oxygen to the blood has been reduced below working levels
A) Syncope
B) Come
C) Asphyxia
D) Homicide
  • 27. The hair belong to human if the medulla is
A) Greater than 0.5
B) Less than 0.5
C) one of these
D) Approximately 0.5
  • 28. If the specimen show positive results of presence of blood .what color will appear immediately after performing quaiacum test for blood
A) Beautiful Blue
B) Intense blue
C) Rose red
  • 29. It's contains the most information about the hair
A) Head hair
B) Facial hair
C) Hair shaft
D) Tip
  • 30. 14. The medical dessection and examination of a body in order to determine the cause of death is.
A) Autopsy
B) Death Certificate
C) Exhumation
D) Cadaric Spasm
  • 31. How long after death can a toxicology report be done
A) 4 to 6 weeks
B) 4 to 5 weeks
C) 5 to 7 weeks
  • 32. This test is almost specific for human semen
A) Barberi'o test
B) Acid phosphatase test
C) Florence test
D) None of these
  • 33. Blood is red in color due to the present to:
A) Platelets
B) Serum
C) Hemoglobin
  • 34. What is the must widely used method for finding invisible blood
A) The kastle-Meyer
B) Luminol Test
C) Takayama
D) Luminol test
  • 35. The medical condition of a man whose semen condition no sperm
A) Spermatozoa
B) Azoospermia
C) Oligospermia
  • 36. What is forensic toxicology?
A) Study of poisons only
B) Application of toxicology to aid in crime investigation
C) Analysis of drugs in sports
  • 37. What is the primary goal of forensic toxicology?
A) Determine presence and effect of toxic substances in crimes
B) Study environmental toxins
C) Develop new medications
D) Identify diseases
  • 38. What types of samples are commonly analyzed in forensic toxicology
A) Blood, urine, hair, tissue
B) Plants and chemicals
C) Food and cosmetics
  • 39. What is post-mortem toxicology?
A) Analysis of toxic substances in deceased individuals
B) Study of poison antidotes
C) Investigation of workplace accidents
  • 40. What is the role of gas chromatography-mass spectrometry (GC-MS) in forensic toxicology?
A) Analyze DNA
B) Separate and identify volatile compounds
C) Measure pH levels
  • 41. What is the difference between a screening test and a confirmatory test?
A) Screening is final, confirmatory is preliminary
B) Screening is for drugs, confirmatory is for poisons
C) Screening is preliminary, confirmatory is specific
  • 42. What is the significance of the LOD (Limit of Detection) in toxicology testing?
A) Measures drug efficacy
B) Lowest concentration of a substance detectable
C) Indicates maximum safe dose
  • 43. What is a common matrix for drug testing?
A) Urine
B) Bones
C) Salaiva
D) Hair
  • 44. How does hair analysis contribute to forensic Toxicology
A) Provides historical record of drug exposure
B) Detects poison
C) measure impairment
  • 45. What is the purpose of chain of custody in toxicology testing
A) mo maximize evidence
B) Ensure sample integrity and admissibility in court
C) to reduce cost
  • 46. What is an adulterant in urine drug testing?
A) preservative
B) test enhancer
C) Substance added to mask test results
  • 47. What is the significance of metabolite analysis in toxicology?
A) Determines drug potency
B) Identifies antidotes
C) Helps determine drug use history
  • 48. How does alcohol affect the body in acute intoxication
A) Depresses CNS
B) Stimulates CNS
C) Enhances vision
  • 49. What is BAC (Blood Alcohol Concentration)?
A) Test for drugs
B) Measure of liver function
C) Percentage of alcohol in blood
  • 50. What is the Widmark formula used for?
A) Identify poisons
B) Calculate drug dosage
C) Estimate BAC
  • 51. What are common post-mortem changes affecting toxicology results?
A) Enhanced drug effects
B) Redistribution and decomposition
C) Increased metabolism
  • 52. What is the role of LC-MS/MS in forensic toxicology?*
A) Sensitive detection of drugs and metabolites
B) Detect explosives
C) Analyze metals
  • 53. How does tolerance impact toxicology interpretation?
A) Reduces drug efficacy
B) Lowers drug levels
C) Affects interpretation of drug levels and impairment
  • 54. What is the significance of the therapeutic index?
A) Indicates safety margin between efficacy and toxicity
B) Defines LOD
C) Identifies antidotes
D) Measures drug potency
  • 55. What is a poison, in toxicological terms?* A: Any medication
A) Substance causing harmful physiological effects
B) Legal drugs only
C) Only heavy metals
  • 56. The mechanism of toxicity of carbon monoxide is:
A) Pulmonary edema
B) Formation of carboxyhemoglobin
C) inhibition of cytochrome oxidase
  • 57. Formic acid is the toxic metabolite responsible for complications in:
A) Acetone poisoning
B) Ethylene glycol poisoning
C) Methanol poisoning
  • 58. The most common route of exposure in occupational lead poisoning is:
A) Inhalation
B) Skin absorption
C) Ingestion
  • 59. 1.It is a quick and simple method used to identify different types of textile fibers based when exposed to Ultraviolet Light.
A) Burning or Ignition Test
B) Microscopic Examination
C) Flourescent Test
  • 60. Animal Fibers exhibit a_________when exposed to UV light.
A) Green fluorescencelp-045r
B) .Pink fluorescence
C) .Bluish fluorescence
  • 61. A forensic scientist is analyzing DNA from a crime scene. Which of the following sources would provide the most reliable DNA sample?
A) A bloodstain on the victim's clothing
B) A fingernail clipping from the suspect
C) A bloodstain on the victim's clothing
D) A strand of hair without the root
  • 62. A forensic toxicologist is investigating a case of suspected alcohol poisoning. Which analytical method is MOST commonly used to determine the blood alcohol concentration?
A) Ultraviolet-visible spectrophotometry
B) Colorimetric assay
C) Immunoassay
D) Gas chromatography
  • 63. A forensic chemist is analyzing a sample of ink from a ransom note. Which of the following techniques would be MOST useful for comparing the ink to a reference sample?
A) Thin-layer chromatography
B) Visual examination
C) Ultraviolet-visible spectrophotometry
D) Microspectrophotometry
  • 64. A forensic toxicologist is analyzing a blood sample from a deceased individual. Initial screening indicates the presence of a benzodiazepine. To confirm the specific drug and its concentration, which technique should be used?
A) Immunoassay
B) Color spot test
C) Ultraviolet-visible spectrophotometry
D) Gas chromatography-mass spectrometry
  • 65. A forensic chemist receives a sample of white powder from a crime scene. Preliminary tests suggest the presence of an opioid. Which of the following analytical techniques would be MOST appropriate for confirming the specific type of opioid present and quantifying its concentration?
A) Immunoassay
B) Gas chromatography-mass spectrometry
C) Thin-layer chromatography
D) Microcrystal test
  • 66. A forensic scientist is examining a fiber sample found on a victim's clothing. Which of the following techniques would be MOST useful for identifying the type of fiber?
A) Burn test
B) Solubility test
C) Infrared spectroscopy
D) Microscopic examination
  • 67. A forensic chemist is analyzing a sample of lubricant from a sexual assault case. Which of the following techniques would be MOST useful for identifying the type of lubricant?
A) Microscopic examination
B) Gas chromatography-mass spectrometry
C) Visual examination
D) Infrared spectroscopy
  • 68. Which of the following is a type of biological matrix that can be used for drug testing?
A) All of the above
B) Blood
C) Hair
D) Urine
  • 69. What is the purpose of quality control in forensic toxicology?
A) To reduce the cost of testing
B) To minimize the amount of sample needed
C) To speed up the testing process
D) To ensure the accuracy and reliability of the results
  • 70. Which of the following is a common route of exposure to toxins?
A) All of the above
B) Inhalation
C) Skin absorption
D) Ingestion
  • 71. Which of the following is a limitation of immunoassay screening tests?
A) They are very expensive
B) They can produce false positive results
C) They require a large sample volume
D) They are not sensitive enough to detect low concentrations of drugs
  • 72. What is the purpose of a screening test in forensic toxicology?
A) To quantify the exact amount of a drug in a sample
B) To determine the mechanism of action of a drug
C) To confirm the identity of a drug with absolute certainty
D) To quickly identify the possible presence of drugs or poisons
  • 73. What is the term for the study of the adverse effects of chemical, physical, or biological agents on living organisms?
A) Pathology
B) Physiology
C) Toxicology
D) Pharmacology
  • 74. Which of the following is a common method for collecting breath samples for alcohol testing?
A) Blood draw
B) Saliva swab
C) Breathalyzer
D) Urine collection
  • 75. Which of the following is a common preservative used for blood samples in forensic toxicology?
A) Hydrochloric acid
B) Sodium fluoride
C) Acetic acid
D) Sodium chloride
  • 76. Which analytical technique is often used as a confirmatory test in forensic toxicology?
A) Thin-layer chromatograph
B) Colorimetric assay
C) Gas chromatography-mass spectrometry
D) Immunoassay
  • 77. What type of sample is MOST commonly used in forensic toxicology for initial screening?
A) Bone
B) Hair
C) Tissue
D) Urine
  • 78. Which of the following is NOT a primary goal of forensic toxicology?
A) Determining the effects of drugs and poisons on the human body
B) Identifying the presence of drugs and poisons in biological samples
C) Providing medical treatment to individuals who have been poisoned
D) Interpreting the findings in a legal context
  • 79. Which of the following is an example of a volatile substance that may be analyzed in forensic toxicology?
A) Aspirin
B) Diazepam
C) Morphine
D) Ethanol
  • 80. What is the role of a toxicologist in a death investigation?
A) To analyze biological samples for the presence of drugs and poisons
B) To determine the cause of death
C) To perform the autopsy
D) To interview witnesses
  • 81. What is the role of forensic toxicology in drug-facilitated sexual assault cases?
A) To determine the cause of death
B) To identify the perpetrator
C) To provide counseling to the victim
D) To detect the presence of drugs that may have been used to incapacitate the victim
  • 82. A forensic toxicologist is analyzing a blood sample for the presence of cyanide. What specific precaution is MOST important during sample collection and handling?
A) Immediate freezing of the sample
B) Collection in a tube with sodium fluoride
C) Use of a preservative to prevent degradation
D) Collection in a heparinized tube
  • 83. A person is found dead with a syringe near the body. What is the FIRST step in the toxicological analysis?
A) Obtain blood and urine samples
B) Perform a full autopsy
C) Collect and analyze the syringe contents
D) Conduct a scene investigation
  • 84. A body is exhumed several years after burial. Which tissue is MOST likely to provide reliable toxicology results?
A) Brain
B) Liver
C) Hair
D) Muscle
  • 85. What is the primary purpose of performing a drug extraction in forensic toxicology?
A) To concentrate the drug of interest and remove interfering substances
B) To dilute the sample
C) To calibrate the analytical instrument
D) To preserve the sample for future testing
  • 86. Which of the following best describes the term "pharmacokinetics"?
A) The study of the effects of drugs on the body
B) The study of the chemical structure of drugs
C) The study of drug interactions
D) The study of how the body absorbs, distributes, metabolizes, and eliminates drugs
  • 87. Which of the following is a common "false positive" result in drug screening?
A) An inconclusive result
B) An accurate result
C) A negative result when drugs are present
D) A positive result when drugs are not present
  • 88. Which type of sample is often used for workplace drug testing programs?
A) Urine
B) Hair
C) Saliva
D) Blood
  • 89. A body is found in a remote forest. Insect activity suggests the person died several weeks ago. What sample is MOST useful for toxicology testing?
A) Bone marrow
B) Vitreous humor
C) Fresh blood
D) Urine
  • 90. A body is exhumed several years after burial. Which tissue is MOST likely to provide reliable toxicology results?
A) Liver
B) Hair
C) Muscle
D) Brain
  • 91. Which analytical technique is most widely accepted as the confirmatory test in forensic toxicology?
A) Thin Layer Chromatography (TLC)
B) Gas Chromatography–Mass Spectrometry (GC-MS)
  • 92. Which poison classically causes garlic-like odor from the body?
A) Lead
B) Arsenic
C) Mercury
  • 93. Which specimen is most resistant to postmortem decomposition and useful for long-term drug detection?
A) Saliva
B) Urine
C) Hair
  • 94. Which branch of forensic toxicology deals with drug use in criminal investigations such as DUI cases?
A) Fire-related deaths
B) Environmental toxicology
C) Human performance toxicology
  • 95. Carbon monoxide poisoning is commonly associated with which type of crime?
A) Theft
B) Fire-related deaths
C) Sexual assault
  • 96. In a suspected drug-facilitated sexual assault case reported after 48 hours, the most useful sample for toxicological analysis would be:
A) urine
B) blood
C) hair
  • 97. A suspect claims he was not intoxicated during a crime. Which toxicological test result is most legally reliable to assess impairment at the time of offense?
A) Saliva test
B) Urine drug screen
C) Blood toxicology report
  • 98. In homicide investigations, forensic toxicology mainly helps to establish:
A) Cause and role of toxic substances in dea
B) Criminal intent
C) Identity of the offender
  • 99. Forensic toxicology evidence is most useful in criminology to establish:
A) Presence and role of toxic substances in a crime
B) Crime scene reconstruction
C) Criminal intent
  • 100. A delayed onset of blindness after intoxication is characteristic of poisoning by:
A) Ethanol
B) Methanol
C) Carbon monoxide
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