FS_FCTOXI
  • 1. Which route of entry produces the fastest effect?
    Oral
    Dermal
    Inhalation
    Rectal
A) Inhalation
B) Oral
C) Dermal
D) Rectal
E) Inhalation
  • 2. Forensic toxicology is best defined as the study of:
A) Poisons in industrial work
B) Drugs used in medicine
C) Toxic substances in relation to law
D) Chemical reactions in the body
  • 3. Which professional is responsible for analyzing drugs and poisons for court purposes?
A) forensic Pathologist
B) Medical technologist
C) Forensic toxicologist
D) Chemist
  • 4. Which of the following is NOT a branch of forensic toxicology?
A) Postmortem toxicology
B) Forensic drug testing
C) Clinical pharmacology
D) Human performance toxicology
  • 5. Forensic toxicology is MOST applicable in which investigation?
A) Poisoning
B) Forgery
C) Arson
D) Theft
  • 6. A poison is a substance that
A) Is synthetic
B) Is illegal
C) Is always fatal
D) Produces harmful effects when introduced into the body
  • 7. Which is classified as a mineral poison?
A) Morphine
B) Arsenic
C) . Nicotine
D) Cocaine
  • 8. Carbon monoxide is classified as a:
A) Metallic poison
B) Solid poison
C) Gaseous poison
D) Volatile liquid
  • 9. Acute poisoning means exposure that is:
A) Long-term
B) Repeated
C) Occupational
D) Sudden and short-term
  • 10. Distribution refers to the:
A) Breakdown of drugs
B) Removal of drugs
C) Movement of drugs in the body
D) Entry of drugs into blood
  • 11. The BEST blood sample in postmortem toxicology is:
A) . Cardiac blood
B) Femoral blood
C) Pulmonary blood
D) Jugular blood
  • 12. Decomposition may cause toxicology results to be:
A) Misleading
B) Unaffected
C) Faster
D) More accurate
  • 13. Long-term drug use is best detected using:
A) Hair
B) Saliva
C) Urine
D) Blood
  • 14. Which specimen best reflects recent drug use?
A) Blood
B) Bone
C) Hair
D) Nails
  • 15. Forensic toxicology is MOST important in which crime?
A) Cybercrime
B) Drug-related offenses
C) Kidnapping
D) Estafa
  • 16. A toxicologist testifying in court is called a(n):
  • 17. A toxicologist testifying in court is called a(n):
A) Cyanide
B) Mercury
C) Expert witness
D) Arsenic
  • 18. Forensic toxicology is MOST concerned with:
A) . Chemical synthesis
B) Drug marketing
C) Legal interpretation of poisons
D) Medical treatment
  • 19. The ultimate goal of forensic toxicology is to:
A) Discover new drugs
B) Support justice through science
C) Examination of his testimony
  • 20. Most common sample for resent drugs or alcohol use
A) Semen
B) Tissue
C) . Blood and Urine
D) Hair
  • 21. The most common sample used for drug test
A) Urine
B) saliva
C) Hashis
  • 22. A condition whrein males have no spermatozoa at all in their seminal fluid
A) Anemia
B) Oligospermia
C) Aspermia
  • 23. Application of benzidine test it gives what color?
A) Blue
B) White
C) Yellow
  • 24. In what mode of administration paison by causing production of sweat
A) Inhalation
B) Oral
C) Anal
D) Injection
  • 25. Which evidence offers strongest resistance to decomposition
A) Blood
B) Semen
C) Urine
D) Hair
  • 26. A condition in which the supply of oxygen to the blood has been reduced below working levels
A) Come
B) Syncope
C) Homicide
D) Asphyxia
  • 27. The hair belong to human if the medulla is
A) Less than 0.5
B) Greater than 0.5
C) one of these
D) Approximately 0.5
  • 28. If the specimen show positive results of presence of blood .what color will appear immediately after performing quaiacum test for blood
A) Beautiful Blue
B) Rose red
C) Intense blue
  • 29. It's contains the most information about the hair
A) Facial hair
B) Hair shaft
C) Head hair
D) Tip
  • 30. 14. The medical dessection and examination of a body in order to determine the cause of death is.
A) Cadaric Spasm
B) Death Certificate
C) Exhumation
D) Autopsy
  • 31. How long after death can a toxicology report be done
A) 4 to 5 weeks
B) 5 to 7 weeks
C) 4 to 6 weeks
  • 32. This test is almost specific for human semen
A) None of these
B) Florence test
C) Acid phosphatase test
D) Barberi'o test
  • 33. Blood is red in color due to the present to:
A) Serum
B) Platelets
C) Hemoglobin
  • 34. What is the must widely used method for finding invisible blood
A) Luminol Test
B) Takayama
C) The kastle-Meyer
D) Luminol test
  • 35. The medical condition of a man whose semen condition no sperm
A) Oligospermia
B) Spermatozoa
C) Azoospermia
  • 36. What is forensic toxicology?
A) Study of poisons only
B) Application of toxicology to aid in crime investigation
C) Analysis of drugs in sports
  • 37. What is the primary goal of forensic toxicology?
A) Study environmental toxins
B) Determine presence and effect of toxic substances in crimes
C) Develop new medications
D) Identify diseases
  • 38. What types of samples are commonly analyzed in forensic toxicology
A) Plants and chemicals
B) Blood, urine, hair, tissue
C) Food and cosmetics
  • 39. What is post-mortem toxicology?
A) Study of poison antidotes
B) Analysis of toxic substances in deceased individuals
C) Investigation of workplace accidents
  • 40. What is the role of gas chromatography-mass spectrometry (GC-MS) in forensic toxicology?
A) Separate and identify volatile compounds
B) Analyze DNA
C) Measure pH levels
  • 41. What is the difference between a screening test and a confirmatory test?
A) Screening is for drugs, confirmatory is for poisons
B) Screening is final, confirmatory is preliminary
C) Screening is preliminary, confirmatory is specific
  • 42. What is the significance of the LOD (Limit of Detection) in toxicology testing?
A) Indicates maximum safe dose
B) Measures drug efficacy
C) Lowest concentration of a substance detectable
  • 43. What is a common matrix for drug testing?
A) Salaiva
B) Bones
C) Hair
D) Urine
  • 44. How does hair analysis contribute to forensic Toxicology
A) measure impairment
B) Provides historical record of drug exposure
C) Detects poison
  • 45. What is the purpose of chain of custody in toxicology testing
A) to reduce cost
B) Ensure sample integrity and admissibility in court
C) mo maximize evidence
  • 46. What is an adulterant in urine drug testing?
A) preservative
B) test enhancer
C) Substance added to mask test results
  • 47. What is the significance of metabolite analysis in toxicology?
A) Determines drug potency
B) Helps determine drug use history
C) Identifies antidotes
  • 48. How does alcohol affect the body in acute intoxication
A) Stimulates CNS
B) Enhances vision
C) Depresses CNS
  • 49. What is BAC (Blood Alcohol Concentration)?
A) Measure of liver function
B) Percentage of alcohol in blood
C) Test for drugs
  • 50. What is the Widmark formula used for?
A) Estimate BAC
B) Calculate drug dosage
C) Identify poisons
  • 51. What are common post-mortem changes affecting toxicology results?
A) Enhanced drug effects
B) Increased metabolism
C) Redistribution and decomposition
  • 52. What is the role of LC-MS/MS in forensic toxicology?*
A) Detect explosives
B) Analyze metals
C) Sensitive detection of drugs and metabolites
  • 53. How does tolerance impact toxicology interpretation?
A) Reduces drug efficacy
B) Lowers drug levels
C) Affects interpretation of drug levels and impairment
  • 54. What is the significance of the therapeutic index?
A) Indicates safety margin between efficacy and toxicity
B) Identifies antidotes
C) Measures drug potency
D) Defines LOD
  • 55. What is a poison, in toxicological terms?* A: Any medication
A) Substance causing harmful physiological effects
B) Only heavy metals
C) Legal drugs only
  • 56. The mechanism of toxicity of carbon monoxide is:
A) Formation of carboxyhemoglobin
B) inhibition of cytochrome oxidase
C) Pulmonary edema
  • 57. Formic acid is the toxic metabolite responsible for complications in:
A) Methanol poisoning
B) Ethylene glycol poisoning
C) Acetone poisoning
  • 58. The most common route of exposure in occupational lead poisoning is:
A) Ingestion
B) Skin absorption
C) Inhalation
  • 59. 1.It is a quick and simple method used to identify different types of textile fibers based when exposed to Ultraviolet Light.
A) Flourescent Test
B) Burning or Ignition Test
C) Microscopic Examination
  • 60. Animal Fibers exhibit a_________when exposed to UV light.
A) .Pink fluorescence
B) Green fluorescencelp-045r
C) .Bluish fluorescence
  • 61. A forensic scientist is analyzing DNA from a crime scene. Which of the following sources would provide the most reliable DNA sample?
A) A bloodstain on the victim's clothing
B) A strand of hair without the root
C) A fingernail clipping from the suspect
D) A bloodstain on the victim's clothing
  • 62. A forensic toxicologist is investigating a case of suspected alcohol poisoning. Which analytical method is MOST commonly used to determine the blood alcohol concentration?
A) Immunoassay
B) Ultraviolet-visible spectrophotometry
C) Gas chromatography
D) Colorimetric assay
  • 63. A forensic chemist is analyzing a sample of ink from a ransom note. Which of the following techniques would be MOST useful for comparing the ink to a reference sample?
A) Microspectrophotometry
B) Thin-layer chromatography
C) Ultraviolet-visible spectrophotometry
D) Visual examination
  • 64. A forensic toxicologist is analyzing a blood sample from a deceased individual. Initial screening indicates the presence of a benzodiazepine. To confirm the specific drug and its concentration, which technique should be used?
A) Immunoassay
B) Ultraviolet-visible spectrophotometry
C) Color spot test
D) Gas chromatography-mass spectrometry
  • 65. A forensic chemist receives a sample of white powder from a crime scene. Preliminary tests suggest the presence of an opioid. Which of the following analytical techniques would be MOST appropriate for confirming the specific type of opioid present and quantifying its concentration?
A) Microcrystal test
B) Immunoassay
C) Gas chromatography-mass spectrometry
D) Thin-layer chromatography
  • 66. A forensic scientist is examining a fiber sample found on a victim's clothing. Which of the following techniques would be MOST useful for identifying the type of fiber?
A) Solubility test
B) Microscopic examination
C) Infrared spectroscopy
D) Burn test
  • 67. A forensic chemist is analyzing a sample of lubricant from a sexual assault case. Which of the following techniques would be MOST useful for identifying the type of lubricant?
A) Infrared spectroscopy
B) Gas chromatography-mass spectrometry
C) Microscopic examination
D) Visual examination
  • 68. Which of the following is a type of biological matrix that can be used for drug testing?
A) All of the above
B) Blood
C) Urine
D) Hair
  • 69. What is the purpose of quality control in forensic toxicology?
A) To reduce the cost of testing
B) To ensure the accuracy and reliability of the results
C) To speed up the testing process
D) To minimize the amount of sample needed
  • 70. Which of the following is a common route of exposure to toxins?
A) Inhalation
B) Skin absorption
C) Ingestion
D) All of the above
  • 71. Which of the following is a limitation of immunoassay screening tests?
A) They are very expensive
B) They can produce false positive results
C) They are not sensitive enough to detect low concentrations of drugs
D) They require a large sample volume
  • 72. What is the purpose of a screening test in forensic toxicology?
A) To confirm the identity of a drug with absolute certainty
B) To quantify the exact amount of a drug in a sample
C) To determine the mechanism of action of a drug
D) To quickly identify the possible presence of drugs or poisons
  • 73. What is the term for the study of the adverse effects of chemical, physical, or biological agents on living organisms?
A) Toxicology
B) Pharmacology
C) Pathology
D) Physiology
  • 74. Which of the following is a common method for collecting breath samples for alcohol testing?
A) Saliva swab
B) Blood draw
C) Urine collection
D) Breathalyzer
  • 75. Which of the following is a common preservative used for blood samples in forensic toxicology?
A) Acetic acid
B) Sodium fluoride
C) Sodium chloride
D) Hydrochloric acid
  • 76. Which analytical technique is often used as a confirmatory test in forensic toxicology?
A) Thin-layer chromatograph
B) Immunoassay
C) Gas chromatography-mass spectrometry
D) Colorimetric assay
  • 77. What type of sample is MOST commonly used in forensic toxicology for initial screening?
A) Hair
B) Urine
C) Tissue
D) Bone
  • 78. Which of the following is NOT a primary goal of forensic toxicology?
A) Identifying the presence of drugs and poisons in biological samples
B) Determining the effects of drugs and poisons on the human body
C) Providing medical treatment to individuals who have been poisoned
D) Interpreting the findings in a legal context
  • 79. Which of the following is an example of a volatile substance that may be analyzed in forensic toxicology?
A) Aspirin
B) Ethanol
C) Morphine
D) Diazepam
  • 80. What is the role of a toxicologist in a death investigation?
A) To interview witnesses
B) To determine the cause of death
C) To perform the autopsy
D) To analyze biological samples for the presence of drugs and poisons
  • 81. What is the role of forensic toxicology in drug-facilitated sexual assault cases?
A) To determine the cause of death
B) To detect the presence of drugs that may have been used to incapacitate the victim
C) To identify the perpetrator
D) To provide counseling to the victim
  • 82. A forensic toxicologist is analyzing a blood sample for the presence of cyanide. What specific precaution is MOST important during sample collection and handling?
A) Collection in a tube with sodium fluoride
B) Use of a preservative to prevent degradation
C) Collection in a heparinized tube
D) Immediate freezing of the sample
  • 83. A person is found dead with a syringe near the body. What is the FIRST step in the toxicological analysis?
A) Perform a full autopsy
B) Conduct a scene investigation
C) Collect and analyze the syringe contents
D) Obtain blood and urine samples
  • 84. A body is exhumed several years after burial. Which tissue is MOST likely to provide reliable toxicology results?
A) Hair
B) Brain
C) Muscle
D) Liver
  • 85. What is the primary purpose of performing a drug extraction in forensic toxicology?
A) To concentrate the drug of interest and remove interfering substances
B) To dilute the sample
C) To preserve the sample for future testing
D) To calibrate the analytical instrument
  • 86. Which of the following best describes the term "pharmacokinetics"?
A) The study of the effects of drugs on the body
B) The study of drug interactions
C) The study of the chemical structure of drugs
D) The study of how the body absorbs, distributes, metabolizes, and eliminates drugs
  • 87. Which of the following is a common "false positive" result in drug screening?
A) A negative result when drugs are present
B) An inconclusive result
C) An accurate result
D) A positive result when drugs are not present
  • 88. Which type of sample is often used for workplace drug testing programs?
A) Hair
B) Blood
C) Urine
D) Saliva
  • 89. A body is found in a remote forest. Insect activity suggests the person died several weeks ago. What sample is MOST useful for toxicology testing?
A) Vitreous humor
B) Urine
C) Fresh blood
D) Bone marrow
  • 90. A body is exhumed several years after burial. Which tissue is MOST likely to provide reliable toxicology results?
A) Hair
B) Muscle
C) Liver
D) Brain
  • 91. Which analytical technique is most widely accepted as the confirmatory test in forensic toxicology?
A) Thin Layer Chromatography (TLC)
B) Gas Chromatography–Mass Spectrometry (GC-MS)
  • 92. Which poison classically causes garlic-like odor from the body?
A) Lead
B) Mercury
C) Arsenic
  • 93. Which specimen is most resistant to postmortem decomposition and useful for long-term drug detection?
A) Urine
B) Hair
C) Saliva
  • 94. Which branch of forensic toxicology deals with drug use in criminal investigations such as DUI cases?
A) Fire-related deaths
B) Human performance toxicology
C) Environmental toxicology
  • 95. Carbon monoxide poisoning is commonly associated with which type of crime?
A) Theft
B) Sexual assault
C) Fire-related deaths
  • 96. In a suspected drug-facilitated sexual assault case reported after 48 hours, the most useful sample for toxicological analysis would be:
A) urine
B) blood
C) hair
  • 97. A suspect claims he was not intoxicated during a crime. Which toxicological test result is most legally reliable to assess impairment at the time of offense?
A) Saliva test
B) Blood toxicology report
C) Urine drug screen
  • 98. In homicide investigations, forensic toxicology mainly helps to establish:
A) Cause and role of toxic substances in dea
B) Identity of the offender
C) Criminal intent
  • 99. Forensic toxicology evidence is most useful in criminology to establish:
A) Crime scene reconstruction
B) Criminal intent
C) Presence and role of toxic substances in a crime
  • 100. A delayed onset of blindness after intoxication is characteristic of poisoning by:
A) Methanol
B) Ethanol
C) Carbon monoxide
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