Biopsy - Quiz
  • 1. Who introduced the word 'biopsie' to the medical community in 1879?
A) Marie Curie
B) Abulcasis
C) Ernest Besnier
D) Louis Pasteur
  • 2. What does the Greek word 'bios' mean?
A) Sight
B) Death
C) Life
D) Tissue
  • 3. Which ancient physician developed one of the earliest diagnostic biopsies?
A) Galen
B) Abulcasis
C) Avicenna
D) Hippocrates
  • 4. What is an excisional biopsy?
A) A blood test for cancer
B) Removal of an entire lump or suspicious area
C) A scan of the tumor site
D) Removal of a small cell cluster
  • 5. What is examined in a biopsy specimen to see if the disease has spread beyond the biopsied area?
A) Blood vessel density
B) Cell nucleus
C) Surgical margin
D) The entire organ
  • 6. What does a 'positive margin' indicate in a biopsy?
A) The lesion is benign
B) Disease was found at the edges
C) No further surgery is needed
D) The biopsy was unsuccessful
  • 7. Which biopsy type does not preserve the histological architecture of the tissue cells?
A) Excisional biopsy
B) Fine needle aspiration biopsy
C) Shave biopsy
D) Punch biopsy
  • 8. What is the primary purpose of a liquid biopsy?
A) To perform a deep tissue incision
B) To surgically remove a tumor
C) To examine tissue structure under a microscope
D) To detect cancer cells or substances in body fluid
  • 9. What is a main advantage of cell-free circulating tumor DNA (cfDNA) assays over CTC assays?
A) They can diagnose the site of the tumor
B) There is approximately 100 times more cfDNA than DNA in circulating tumor cells
C) They are cheaper to produce
D) They have zero risk of false negatives
  • 10. Why are liquid biopsies considered an advantage over tissue biopsies regarding tumor genetics?
A) They require no specialized laboratory equipment
B) They provide a better look at tissue architecture
C) They are always 100% accurate
D) They allow for monitoring rapid, dynamic genetic changes
  • 11. What is a major drawback of liquid biopsies?
A) They cannot be used to diagnose cancer
B) They require surgery
C) They involve high radiation exposure
D) They are too painful for the patient
  • 12. What does 'pathologic staging' involve in a mastectomy specimen?
A) Revealing the extent of cancer spread
B) Checking for bacterial infection
C) Removing the skin surface
D) Testing the patient's blood type
  • 13. Which professionals can perform a biopsy?
A) Dentists
B) Nurses
C) Laboratory technicians
D) Medical students
  • 14. In the context of the text, what is a resection?
A) A larger excisional specimen taken by a surgeon to eradicate a known lesion
B) A needle aspiration of fluid
C) A biopsy that only takes a tiny fragment
D) A blood test for tumor DNA
  • 15. What do liquid biopsies analyze to track tumor progression?
A) Biopsy of bone marrow
B) X-ray images of the lungs
C) Circulating tumor cells and cell-free DNA
D) Tissue density in the liver
  • 16. Which artery is frequently biopsied when vasculitis is suspected?
A) Radial artery
B) Carotid artery
C) Temporal artery
D) Femoral artery
  • 17. What is vital in the diagnosis of Crescentic glomerulonephritis?
A) MRI imaging
B) Immunofluorescence
C) Blood glucose testing
D) Genetic sequencing
  • 18. Which condition involves the accumulation of degraded proteins in body tissues?
A) Glomerulonephritis
B) Vasculitis
C) Crohn's disease
D) Amyloidosis
  • 19. Where is a biopsy commonly taken to diagnose amyloidosis?
A) Gingiva
B) Brain
C) Heart
D) Liver
  • 20. Who specializes in diagnosing diseases by examining tissue under a microscope?
A) Surgeon
B) Radiologist
C) General practitioner
D) Pathologist
  • 21. What is done to the biopsy sample at the pathology laboratory to make individual cells more visible?
A) Stained with dyes
B) Dissolved in acid
C) Exposed to radiation
D) Frozen at extreme temperatures
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