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Supercritical Fluid Chromatography - Quiz
  • 1. Which of the following is commonly used as the mobile phase in SFC?
A) Acetone
B) Carbon dioxide
C) Methanol
D) Water
  • 2. What state is the mobile phase in SFC?
A) Liquid
B) Solid
C) Gas
D) Supercritical
  • 3. What is the mechanism of separation in SFC based on?
A) Differences in molecular weight
B) Differences in boiling point
C) Differences in solubility in the mobile phase
D) Differences in conductivity
  • 4. What is the purpose of using a back pressure regulator in SFC?
A) Maintain supercritical conditions
B) Avoid solvent contamination
C) Enhance detector sensitivity
D) Increase column temperature
  • 5. What advantage does SFC offer over traditional HPLC?
A) Limited application range
B) Lower equipment cost
C) Higher resolution
D) Faster separation
  • 6. What role does co-solvent play in SFC separations?
A) Enhances analyte solubility
B) Improves stationary phase selectivity
C) Reduces detector interference
D) Stabilizes column efficiency
  • 7. Which term describes the region where the mobile phase in SFC exhibits properties of both a liquid and a gas?
A) Supercritical zone
B) Transition zone
C) Critical point
D) Near-critical region
  • 8. At supercritical conditions, the density of carbon dioxide is similar to that of which phase?
A) Gas
B) Liquid
C) Aqueous
D) Solid
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