Parkinson-plus syndrome - Quiz
  • 1. What distinguishes Parkinson-plus syndromes from idiopathic Parkinson's disease?
A) Age of onset exclusively under 30
B) Inability to walk
C) Complete lack of tremor
D) Additional clinical features
  • 2. Which of the following is considered a Parkinson-plus syndrome?
A) Huntington's disease
B) Amyotrophic lateral sclerosis
C) Progressive supranuclear palsy
D) Multiple sclerosis
  • 3. How are Parkinson-plus syndromes classified based on pathology?
A) Acute and chronic
B) Genetic and metabolic
C) Primary and secondary
D) Synucleinopathies and tauopathies
  • 4. What is another name for the autonomic failure seen in multiple system atrophy?
A) Pick's disease
B) Supranuclear gaze palsy
C) Corticobasal degeneration
D) Shy–Drager syndrome
  • 5. Which of the following is a clinical feature distinguishing PPS from idiopathic PD?
A) Unilateral tremor
B) Excellent response to levodopa
C) Symmetrical onset
D) Late-onset postural instability
  • 6. What diagnostic tool uses 123I-iodobenzamide to assist in the differential diagnosis of PPS?
A) PET scan
B) SPECT
C) CT scan
D) MRI
  • 7. Which disorder is recognized as the second-most common type of neurodegenerative dementia?
A) Corticobasal degeneration
B) Dementia with Lewy bodies
C) Pick's disease
D) Progressive supranuclear palsy
  • 8. Olivopontocerebellar atrophy is characterized by which symptoms?
A) Ataxia and dysarthria
B) Memory loss and hallucinations
C) Resting tremor and rigidity
D) Alien limb and apraxia
  • 9. How do Parkinson-plus syndromes generally respond to antiparkinsonian medication compared to PD?
A) They show identical response
B) They react negatively to all medication
C) They are less likely to respond
D) They respond significantly better
  • 10. What is the primary approach to therapy for Parkinson-plus syndromes?
A) Curative surgery
B) Multidisciplinary treatment of symptoms
C) High-dose levodopa monotherapy
D) Preventative gene therapy
  • 11. Which of these is a recognized motor feature of Parkinson-plus syndromes?
A) Spontaneous recovery
B) Increased dopamine production
C) Reduced axial muscle rigidity
D) Supranuclear gaze palsy
  • 12. What is the nature of the progression of Parkinson-plus syndromes compared to PD?
A) Stable without progression
B) Reversible
C) More slowly progressive
D) More rapidly progressive
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