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Complete blood count - Quiz
Contributed by: Payne
  • 1. What does point-of-care testing refer to?
A) Tests conducted only by laboratory technicians
B) Tests conducted exclusively in specialized hospitals
C) Tests that require long processing times
D) Tests conducted outside of the laboratory setting
  • 2. Which of the following is a benefit of point-of-care testing?
A) It requires highly specialized personnel
B) It is more expensive than lab tests
C) It is faster than conventional methods
D) It uses more blood than standard tests
  • 3. Where might point-of-care testing be performed?
A) Only in pharmacies
B) Only in a central research laboratory
C) Only in university lecture halls
D) At a person's bedside or in a clinic
  • 4. Which device is mentioned as a portable analyzer for hemoglobin concentration?
A) Microscope
B) HemoCue
C) Centrifuge
D) i-STAT
  • 5. How does the HemoCue measure hemoglobin concentration?
A) By measuring blood conductivity
B) By using manual visual inspection
C) By using spectrophotometry
D) By counting white blood cells
  • 6. How does the i-STAT device derive a hemoglobin reading?
A) By calculating plasma volume
B) By using spectrophotometry
C) By estimating red blood cell concentration from conductivity
D) By counting platelets manually
  • 7. Why is point-of-care testing useful in emergency situations?
A) It is only available in large hospitals
B) It provides a more accurate result than labs
C) It is faster and requires less blood
D) It requires no device calibration
  • 8. What is a potential issue with measuring hemoglobin and hematocrit on blood gas devices?
A) They are too expensive to maintain
B) They cannot measure blood gas levels
C) They require a full laboratory setting
D) The measurements correlate poorly with standard methods
  • 9. What type of personnel is required for point-of-care testing?
A) Only board-certified pathologists
B) Only specialized laboratory scientists
C) Specially trained personnel are not required
D) Only professional phlebotomists
  • 10. Are there simplified hematology analyzers available for clinic use?
A) Yes, but they cannot perform a differential
B) Yes, they can provide a complete blood count and differential
C) No, hematology analyzers are only for labs
D) No, they can only measure hemoglobin
  • 11. What is the technique called where cells are measured as they flow past sensors?
A) Spectrophotometry
B) Hydrodynamic electrophoresis
C) Laminar chromatography
D) Flow cytometry
  • 12. What is the purpose of hydrodynamic focusing?
A) To stain the cell nuclei for easier detection.
B) To chemically lyse the white blood cells.
C) To isolate individual cells into a single file.
D) To increase the concentration of the sample.
  • 13. What is the standard wavelength used to measure hemoglobin absorbance?
A) 540 nanometres
B) 640 nanometres
C) 740 nanometres
D) 340 nanometres
  • 14. Which principle does impedance-based cell counting rely on?
A) Faraday's law
B) Coulter principle
C) Doppler effect
D) Beer-Lambert law
  • 15. In light scattering, what does forward scatter correlate with?
A) Cellular size
B) Cytoplasmic granulation
C) Hemoglobin concentration
D) Nuclear complexity
  • 16. What does side scatter in light scattering techniques reveal?
A) Cellular volume
B) Red blood cell count
C) Cellular complexity
D) Hemoglobin stability
  • 17. Which substance is used to convert hemoglobin into a stable form for measurement?
A) Oxyhemoglobin
B) Cyanmethemoglobin
C) Carboxyhemoglobin
D) Myeloperoxidase
  • 18. What does digital microscopy software use to classify white blood cells?
A) Coulter principle
B) Radiofrequency analysis
C) Fluorescent staining
D) Artificial intelligence
  • 19. What is typically added to the blood collection tube to prevent clotting?
A) Heparin
B) EDTA
C) Sodium citrate
D) Saline
  • 20. From which body site is blood most commonly drawn for a complete blood count?
A) Muscle
B) Bone marrow
C) Artery
D) Vein
  • 21. What is the primary method used for performing a complete blood count?
A) Automated analyzer
B) Centrifugation only
C) Chemical titration
D) Manual observation only
  • 22. Which method is used to collect blood from babies when venous access is difficult?
A) Earlobe prick
B) Heelprick
C) Fingerstick
D) Arterial puncture
  • 23. Which manual technique is mentioned as a way to check abnormal results?
A) Manual hematocrit test
B) Manual coagulation profile
C) Manual platelet aggregation test
D) Manual blood culture
  • 24. Which site can be used for a fingerstick collection if venous access is difficult?
A) Veins
B) Capillaries
C) Lymph nodes
D) Arteries
  • 25. What is another name for a complete blood count?
A) Clinical blood screening
B) Full haemogram
C) Plasma analysis
D) Hematology profile
  • 26. What percentage of blood samples typically require a manual blood smear review?
A) 10–25%
B) 40–50%
C) 1–5%
D) Over 75%
  • 27. Who developed the first procedure for a blood count in 1852?
A) Louis-Charles Malassez
B) Maxwell Wintrobe
C) Wallace H. Coulter
D) Karl Vierordt
  • 28. Which invention simplified microscopic blood cell analysis in 1874?
A) Centrifuge
B) Automated staining slide
C) Hemocytometer
D) Coulter counter
  • 29. What does the Coulter principle utilize to count blood cells?
A) Optical refraction
B) Electrical impedance
C) Chemical titration
D) Fluorescent labeling
  • 30. What is the fluid portion of blood called?
A) Plasma
B) Serum
C) Lymph
D) Interstitial fluid
  • 31. Which treatment for cancer is explicitly noted to suppress bone marrow production?
A) Targeted hormone therapy
B) Chemotherapy
C) Blood thinning medication
D) Immunotherapy
  • 32. Which psychiatric drug is associated with a risk of agranulocytosis?
A) Diazepam
B) Lithium
C) Clozapine
D) Fluoxetine
  • 33. What does a low count of all three cell types indicate?
A) Pancytopenia
B) Anemia
C) Leukemia
D) Thrombocytopenia
  • 34. What percentage of healthy people fall within the established CBC reference ranges?
A) 95%
B) 99%
C) 90%
D) 97%
  • 35. What stain is used for examining a manual blood smear under a microscope?
A) Acid-fast stain
B) Gram stain
C) Wright-Giemsa stain
D) Romanowsky stain
  • 36. The presence of schistocytes on a blood smear is suggestive of which condition?
A) Microangiopathic hemolytic anemia
B) Sickle cell disease
C) Multiple myeloma
D) Malaria
  • 37. What is the term for red blood cells that appear stacked together on a smear?
A) Schistocytes
B) Vacuolation
C) Toxic granulation
D) Rouleaux
  • 38. What is the primary manual method for determining the hematocrit?
A) Using a spectrophotometer
B) Centrifuging a filled capillary tube
C) Measuring blood absorbance on absorbent paper
D) Counting cells in a hemocytometer
  • 39. Which condition can cause automated hematocrit results to be inaccurate due to white blood cells being counted as red cells?
A) Polycythemia
B) Anemia
C) Multiple myeloma
D) Severe leukocytosis
  • 40. Which substance is used to lyse red blood cells when performing a manual white blood cell count?
A) Ammonium oxalate
B) Distilled water
C) Ethanol
D) Saline
  • 41. What type of microscope makes platelets easier to identify during manual counting?
A) Fluorescence microscope
B) Electron microscope
C) Phase-contrast microscope
D) Light microscope
  • 42. What diagnostic feature on a white blood cell can be identified microscopically but not by an automated analyzer?
A) Total count
B) Hemoglobin content
C) Cell size
D) Toxic granulation
  • 43. Which parasitic disease can be detected on a blood smear?
A) Polycythemia
B) Babesiosis
C) Leukemia
D) Multiple myeloma
  • 44. Which parameter is mentioned as particularly useful for moving average measurement?
A) WBC count
B) MCV
C) MCHC
D) Platelet count
  • 45. Are expected results for external quality assessment samples disclosed to the laboratory?
A) No
B) Yes
C) Only if the results are outside the threshold
D) Only upon request
  • 46. Why might some laboratories in under-resourced areas struggle to implement external quality assessment?
A) Inaccurate MCHC values
B) Lack of patient samples
C) Logistical issues
D) Lack of internal quality control
  • 47. Who typically provides the quality control samples for automated analyzers?
A) The laboratory technicians
B) The patients themselves
C) The local hospital board
D) The instrument manufacturer
  • 48. What is the assumption behind using the moving average measurement technique?
A) All patients have the same blood type
B) Patient population characteristics remain roughly the same over time
C) External quality samples are run every day
D) The analyzer resets its own calibration daily
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