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Molecular virology - Exam
Contributed by: Mead
  • 1. Molecular virology is a branch of virology that focuses on studying the genetic material, replication, and interactions of viruses at the molecular level. This field delves into the structure and function of viral components such as nucleic acids, proteins, and membranes, and their intricate roles in viral infection and pathogenesis. By investigating the molecular mechanisms underlying viral replication, host-virus interactions, immune responses, and antiviral strategies, molecular virologists contribute significantly to our understanding of viral diseases and the development of novel therapeutics and vaccines.

    What is a viral capsid?
A) Protein shell that encloses viral genome
B) Energy-producing organelle
C) Lipid membrane surrounding virus
D) Enzyme that breaks down host cell DNA
  • 2. What is a bacteriophage?
A) Virus that infects plants
B) Virus that infects fungi
C) Virus that infects bacteria
D) Virus that infects animals
  • 3. Which enzyme is crucial for retrovirus replication?
A) Reverse transcriptase
B) Ligase
C) DNA polymerase
D) RNA polymerase
  • 4. What is the function of a viral envelope?
A) Produces energy
B) Regulates gene expression
C) Facilitates entry into host cell
D) Protects viral genome
  • 5. What is antigenic drift in viruses?
A) Minor changes in viral proteins over time
B) Mutation in viral replication enzyme
C) Rapid and massive change in viral genome
D) No change in viral structure
  • 6. How do vaccines protect against viral infections?
A) By directly destroying viruses
B) By inhibiting viral replication
C) By triggering the immune system to produce antibodies
D) By increasing viral mutation rate
  • 7. What is the role of a viroporin in virus replication?
A) Forms channels in host cell membrane for viral entry and release
B) Helps virus replicate its genome
C) Promotes immune response against virus
D) Packages viral genome into new virus particles
  • 8. Which virus is responsible for causing AIDS?
A) HIV (Human Immunodeficiency Virus)
B) Herpes Simplex Virus
C) Influenza Virus
D) Rotavirus
  • 9. How do virophages differ from traditional viruses?
A) Contain both DNA and RNA genomes
B) Infect other viruses rather than host cells
C) Are larger in size
D) Replicate outside of host cell
  • 10. Which cellular organelle is often exploited by viruses for replication and assembly of viral particles?
A) Nucleus
B) Mitochondria
C) Endoplasmic reticulum
D) Golgi apparatus
  • 11. Which viral family does the human immunodeficiency virus (HIV) belong to?
A) Picornaviridae
B) Herpesviridae
C) Orthomyxoviridae
D) Retroviridae
  • 12. What is the viral protein that helps to initiate the synthesis of viral RNA from the viral DNA template called?
A) Helicase
B) Primase
C) DNA polymerase
D) RNA polymerase
  • 13. What is the name given to a virus particle outside a host cell that consists of a nucleic acid core surrounded by a protein coat?
A) Capsid
B) Envelope
C) Virion
D) Spike
  • 14. What is the term for a virus that infects bacteria?
A) Phage virus
B) Bacteriophage
C) Prokaryophage
D) Bacterial virus
  • 15. What is the importance of viral receptors in host specificity?
A) Regulates viral protein expression
B) Produces energy for virus
C) Determines which host cells a virus can infect
D) Aids in viral replication
  • 16. What is the term for the process by which viruses acquire new genetic material from different sources?
A) Replication
B) Recombination
C) Translation
D) Mutation
  • 17. What do helical symmetries refer to in viruses?
A) Type of viral envelope
B) Mode of viral transmission
C) Structure of viral capsid proteins arranged in a helix
D) Response of host cells to viral infection
  • 18. Which viral disease has been eradicated through a successful vaccination campaign?
A) Ebola
B) Influenza
C) Polio
D) Smallpox
  • 19. What is the virus that causes COVID-19 classified as?
A) Filovirus
B) Paramyxovirus
C) Rhabdovirus
D) Coronavirus
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