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Chronic kidney disease - Quiz
Contributed by: McLoughlin
  • 1. What is the primary driver of damage in obesity-related CKD?
A) High protein intake
B) Excessive water consumption
C) Low physical activity
D) Visceral obesity
  • 2. How much more likely are high calorie and high fructose beverages to make an individual develop CKD?
A) 75%
B) 50%
C) 60%
D) 30%
  • 3. Which of these is NOT listed as a weight management intervention for CKD?
A) Genetic counseling
B) Dietary changes
C) Surgical interventions
D) Pharmacological interventions
  • 4. What is the effect of reduced salt intake on albuminuria in CKD patients?
A) It fluctuates unpredictably
B) It may help lower it
C) It has no effect
D) It increases it
  • 5. What symptom may be associated with low blood pressure due to salt restriction?
A) Joint pain
B) Dizziness
C) Fever
D) Blurred vision
  • 6. Does Omega-3 supplementation prevent vascular blockage in CKD patients?
A) Yes
B) No
C) Only in dialysis patients
D) Only in early stages
  • 7. What effect do oral protein-based supplements have on serum albumin levels in CKD?
A) They decrease them significantly
B) They stabilize them perfectly
C) They have no effect
D) They may increase them slightly
  • 8. What is the known impact of weight loss interventions on preventing cardiovascular events in CKD patients?
A) It definitely prevents stroke only
B) It prevents all events
C) It increases the risk
D) It is not known
  • 9. Which tool might improve dietary sodium intake and fluid management for CKD patients?
A) EHealth interventions
B) Hospital isolation
C) Complete fasting
D) Daily surgery
  • 10. What is the effect of salt restriction on extracellular fluid and oedema in CKD patients?
A) It increases them
B) It decreases them
C) It eliminates them entirely
D) The effect is unknown
  • 11. What physiological change is linked to potential benefits from protein supplementation in CKD?
A) Decreased blood volume
B) Increased mid-arm muscle circumference
C) Decreased bone density
D) Increased insulin resistance
  • 12. How should weight management interventions for CKD patients be approached?
A) Determined by age alone
B) Based solely on BMI
C) Standardized for all patients
D) Individualized based on assessment
  • 13. For how long must a GFR be below 60 mL/min/1.73 m2 to be defined as chronic kidney disease?
A) 3 months
B) 1 year
C) 6 months
D) 1 month
  • 14. What urine albumin/creatinine ratio (ACR) value is used to define kidney damage?
A) ≥ 50
B) ≥ 60
C) ≥ 15
D) ≥ 30
  • 15. What does the letter 'P' signify in British guidelines for chronic kidney disease?
A) Persistent filtration loss
B) Potentially reversible damage
C) Significant protein loss
D) Primary renal failure
  • 16. What is the GFR range for Stage 3A chronic kidney disease according to British guidelines?
A) 60–89 mL/min/1.73 m2
B) 45–59 mL/min/1.73 m2
C) 15–29 mL/min/1.73 m2
D) 30–44 mL/min/1.73 m2
  • 17. What is the GFR range for Stage 3B chronic kidney disease according to British guidelines?
A) 60–89 mL/min/1.73 m2
B) 15–29 mL/min/1.73 m2
C) 45–59 mL/min/1.73 m2
D) 30–44 mL/min/1.73 m2
  • 18. What characterizes Stage 4 chronic kidney disease?
A) Established kidney failure
B) Normal GFR with albuminuria
C) Slightly diminished function
D) Severe reduction in GFR (15–29 mL/min/1.73 m2)
  • 19. What is the GFR threshold for Stage 5 chronic kidney disease?
A) <15 mL/min/1.73 m2
B) <45 mL/min/1.73 m2
C) <30 mL/min/1.73 m2
D) <60 mL/min/1.73 m2
  • 20. Which term describes persons with CKD who do not yet require kidney replacement therapy?
A) Acute renal failure
B) End-stage renal replacement
C) ESKD
D) NDD-CKD
  • 21. What does ESKD stand for?
A) Excessive sodium kidney disorder
B) Established syndrome kidney damage
C) Early stage kidney dysfunction
D) End-stage kidney disease
  • 22. What are the two types of kidney replacement therapy mentioned in the text?
A) Dietary changes or dialysis
B) Dialysis or transplantation
C) Transplantation or dietary therapy
D) Medication or surgery
  • 23. Is a person with Stage 5 CKD who has not started replacement therapy considered NDD-CKD?
A) Only if protein loss is absent
B) No
C) Only if GFR is > 20
D) Yes
  • 24. Protein in the urine is an independent marker for which two conditions?
A) Worsening kidney function and cardiovascular disease
B) High blood pressure and diabetes
C) Dialysis dependence and organ failure
D) Stage 1 CKD and Stage 5 CKD
  • 25. Which of the following is a common early indicator of CKD before symptoms appear?
A) Vomiting
B) Severe leg swelling
C) Proteinuria
D) Confusion
  • 26. What is a primary diagnostic test used to measure kidney function?
A) Skin biopsy
B) ECG
C) Blood pressure check
D) Estimated glomerular filtration rate (eGFR)
  • 27. Which condition is a leading cause of chronic kidney disease?
A) Skin infections
B) Diabetes
C) Asthma
D) Fractures
  • 28. What is the term for the crystallization of urea on the skin?
A) Edema
B) Uremic frost
C) Azotemia
D) Cachexia
  • 29. Which electrolyte abnormality is associated with cardiac arrhythmias in CKD patients?
A) Hypocalcemia
B) Hypernatremia
C) Hyperkalemia
D) Hyponatremia
  • 30. Which medication type should be avoided in patients with CKD?
A) ACEIs
B) NSAIDs
C) Loop diuretics
D) ARBs
  • 31. What is a major complication of CKD relating to red blood cell production?
A) Metabolic acidosis
B) Hyperphosphatemia
C) Insulin resistance
D) Anemia
  • 32. What is the recommended dietary approach for patients with CKD?
A) Ultraprocessed foods
B) Plant-based foods
C) Low carbohydrate ketogenic diet
D) High animal-based protein diet
  • 33. What is the leading cause of death associated with CKD mentioned in the data?
A) Diabetes
B) Cardiovascular complications
C) Glomerulonephritis
D) High blood pressure
  • 34. What term is used for CKD when the cause is unknown?
A) Obstructive
B) Idiopathic
C) Ischemic
D) Congenital
  • 35. Which of the following is an example of small-vessel vascular disease?
A) Bilateral kidney artery stenosis
B) Ischemic nephropathy
C) Benign prostatic hyperplasia
D) Polycystic kidney disease
  • 36. Which condition is classified as a primary glomerular disease?
A) Focal segmental glomerulosclerosis
B) Ischemic nephropathy
C) Diabetic nephropathy
D) Lupus nephritis
  • 37. What is a known potential cause of obstructive nephropathy?
A) Lithium treatment
B) Benign prostatic hyperplasia
C) Chronic lead exposure
D) IgA nephropathy
  • 38. Which rare cause of obstructive nephropathy is mentioned in the text?
A) Lead
B) Pinworms
C) Lithium
D) High temperatures
  • 39. What is Mesoamerican nephropathy sometimes called?
A) Obstructive nephropathy
B) Ischemic nephropathy
C) Glomerular nephropathy
D) Agricultural nephropathy
  • 40. Which factor is suspected to cause Mesoamerican nephropathy?
A) Congenital genetic mutations
B) High protein diet
C) Heat stress
D) Bacterial infection
  • 41. After how many years of lithium treatment can chronic kidney disease occur?
A) 10-20 years
B) 1-5 years
C) 5-10 years
D) 20-30 years
  • 42. What percentage of people may develop CKD from long-term lithium treatment?
A) 0.1-0.5%
B) 10-20%
C) 5-10%
D) 1-5%
  • 43. How can kidney harm be mitigated during lithium treatment?
A) Dosing three times per day
B) Avoiding all intake of water
C) Dosing once per day at night
D) Increasing the dose as much as possible
  • 44. Which group is recommended to undergo screening for CKD?
A) Individuals with no family history of illness
B) Healthy adults with no risk factors
C) Children under the age of 10
D) Those with hypertension
  • 45. What is the recommended timing for collecting urine for the albumin-to-creatinine ratio (ACR)?
A) 24-hour urine collection
B) Random urine sample in the evening
C) First-morning urine specimen
D) Urine collected immediately after exercise
  • 46. What is the relationship between GFR and serum creatinine?
A) No correlation
B) Exponential
C) Directly proportional
D) Reciprocal
  • 47. Which radioactive element is used in MAG3 and DMSA scans?
A) Iodine-131
B) Technetium-99
C) Uranium-235
D) Carbon-14
  • 48. Which test is used to confirm blood flow and differential function between the two kidneys?
A) Nuclear medicine MAG3 scan
B) Physical palpation
C) Urine dipstick
D) Serum creatinine measurement
  • 49. What does the GFR measure?
A) The concentration of hormones in the blood
B) The total number of nephrons
C) The size of the ureters
D) How efficiently the glomeruli work
  • 50. Which drug class is recommended to slow CKD progression in adults with an eGFR ≥20 mL/min/1.73 m²?
A) Statins
B) Phosphate binders
C) SGLT2 inhibitors
D) ACEIs
  • 51. What is the recommended target hemoglobin level for patients with anemia in CKD?
A) 120–140 g/L
B) 100–120 g/L
C) 80–100 g/L
D) 140–160 g/L
  • 52. What should be administered prior to treatment with erythropoietin in CKD patients?
A) Oral calcium
B) Parenteral iron
C) Vitamin D supplements
D) Zinc supplements
  • 53. What is the recommended daily protein intake for metabolically stable adults with CKD stages G3–G5?
A) More than 1.3 g/kg
B) Greater than 2.0 g/kg
C) Exactly 0.4 g/kg
D) Approximately 0.8 g/kg
  • 54. Which medication is recommended for the treatment of vitamin D deficiency and metabolic bone disease in CKD?
A) Statins
B) Calcitriol
C) Erythropoietin
D) Dapagliflozin
  • 55. Which of the following is used to control elevated serum phosphate levels in advanced CKD?
A) Phosphate binders
B) Zinc
C) Gadolinium
D) ACEIs
  • 56. Which group of people is a very-low-protein diet NOT recommended for due to growth concerns?
A) Patients with high blood pressure
B) Children
C) Patients with diabetes
D) Elderly patients
  • 57. What is a potential safety risk associated with intravenous iron therapy in CKD patients?
A) Allergic reactions
B) Reduced kidney function
C) Vitamin toxicity
D) Increased blood pressure
  • 58. Which activity may help with sleep regulation and decrease fatigue in CKD patients?
A) Reducing social interaction
B) Drinking coffee
C) Exercise
D) Increasing nocturnal fluid intake
  • 59. What is the current scientific consensus on the effectiveness of treatments for sleep disorders in CKD?
A) Medication is guaranteed to cure sleep disorders
B) Relaxation techniques are highly effective
C) Exercise is the gold standard treatment
D) None of the options have been proven effective
  • 60. At what stage of CKD is referral to a nephrologist generally considered required?
A) Stage 1
B) Stage 4
C) Stage 2
D) Stage 5 only
  • 61. What is a surgical benefit of early nephrology referral for those opting for hemodialysis?
A) Removal of the kidneys
B) Placement of an arteriovenous fistula
C) Transplant of a liver
D) Cardiac bypass surgery
  • 62. What is the cardiovascular disease prevalence in the Medicare population with CKD over age 66?
A) 65%
B) 50%
C) 32%
D) 80%
  • 63. What is a common complication of CKD in children and adolescents?
A) Increased bone density
B) Cognitive decline
C) Growth failure
D) Early puberty
  • 64. Which treatment appears to be associated with improved survival compared to conventional hemodialysis?
A) Medication-only therapy
B) High-intensity home hemodialysis
C) Occasional peritoneal dialysis
D) Low-flux hospital hemodialysis
  • 65. How many people in the U.S. were estimated to have CKD between 2017 and 2020?
A) 25%
B) 10%
C) 8.8%
D) 13.9%
  • 66. What is the primary occupation of those affected by Mesoamerican nephropathy (MeN)?
A) Fishermen
B) Sugarcane labourers
C) Coal miners
D) Office workers
  • 67. Which ethnic group is specifically mentioned as having high hypertension-related ESKD risk?
A) Inuit populations
B) Caucasians
C) African Americans
D) Native Americans
  • 68. What therapy is often required for black patients because standard antihypertensive drugs are less effective?
A) Antibiotic therapy
B) Insulin therapy
C) Dialysis-only therapy
D) Bicarbonate therapy
  • 69. In 2013, how many deaths were attributed to CKD globally?
A) 250,000
B) 956,000
C) 1.2 million
D) 409,000
  • 70. What is the rank of CKDu as a cause of in-hospital mortality in Sri Lanka?
A) Third
B) Eighth
C) Tenth
D) First
  • 71. What percentage of ESKD cases in Caucasians are attributed to high blood pressure?
A) 10%
B) 50%
C) 37%
D) 19%
  • 72. Which UK organization represents kidney physicians and works with the National Service Framework?
A) Kidney Care UK
B) The Renal Association
C) The UK National Kidney Federation
D) The International Society of Nephrology
  • 73. Which dog breed is listed as having one of the highest rates of CKD?
A) Swedish elkhound
B) Boxer
C) Siberian husky
D) Finnish spitz
  • 74. Which dog breed is listed as having one of the lowest rates of CKD?
A) Bernese mountain dog
B) Boxer
C) Miniature schnauzer
D) Siberian husky
  • 75. What condition in cats with CKD can lead to anemia?
A) Weight loss
B) Increased urine volume
C) Acidosis
D) Hypertension
  • 76. Which organization represents nephrology professionals in the United States?
A) The National Kidney Foundation
B) The American Kidney Fund
C) The Renal Physicians Association
D) The American Association of Kidney Patients
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