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Biopsy - Quiz
Contributed by: Burrows
  • 1. Who introduced the word 'biopsie' to the medical community in 1879?
A) Marie Curie
B) Ernest Besnier
C) Abulcasis
D) Louis Pasteur
  • 2. What does the Greek word 'bios' mean?
A) Tissue
B) Sight
C) Death
D) Life
  • 3. Which ancient physician developed one of the earliest diagnostic biopsies?
A) Galen
B) Abulcasis
C) Hippocrates
D) Avicenna
  • 4. What is an excisional biopsy?
A) A scan of the tumor site
B) Removal of a small cell cluster
C) Removal of an entire lump or suspicious area
D) A blood test for cancer
  • 5. What is examined in a biopsy specimen to see if the disease has spread beyond the biopsied area?
A) Blood vessel density
B) The entire organ
C) Surgical margin
D) Cell nucleus
  • 6. What does a 'positive margin' indicate in a biopsy?
A) No further surgery is needed
B) The biopsy was unsuccessful
C) The lesion is benign
D) Disease was found at the edges
  • 7. Which biopsy type does not preserve the histological architecture of the tissue cells?
A) Excisional biopsy
B) Fine needle aspiration biopsy
C) Punch biopsy
D) Shave biopsy
  • 8. What is the primary purpose of a liquid biopsy?
A) To detect cancer cells or substances in body fluid
B) To examine tissue structure under a microscope
C) To perform a deep tissue incision
D) To surgically remove a tumor
  • 9. What is a main advantage of cell-free circulating tumor DNA (cfDNA) assays over CTC assays?
A) There is approximately 100 times more cfDNA than DNA in circulating tumor cells
B) They can diagnose the site of the tumor
C) They are cheaper to produce
D) They have zero risk of false negatives
  • 10. Why are liquid biopsies considered an advantage over tissue biopsies regarding tumor genetics?
A) They are always 100% accurate
B) They allow for monitoring rapid, dynamic genetic changes
C) They require no specialized laboratory equipment
D) They provide a better look at tissue architecture
  • 11. What is a major drawback of liquid biopsies?
A) They require surgery
B) They involve high radiation exposure
C) They are too painful for the patient
D) They cannot be used to diagnose cancer
  • 12. What does 'pathologic staging' involve in a mastectomy specimen?
A) Checking for bacterial infection
B) Revealing the extent of cancer spread
C) Removing the skin surface
D) Testing the patient's blood type
  • 13. Which professionals can perform a biopsy?
A) Nurses
B) Laboratory technicians
C) Medical students
D) Dentists
  • 14. In the context of the text, what is a resection?
A) A larger excisional specimen taken by a surgeon to eradicate a known lesion
B) A biopsy that only takes a tiny fragment
C) A blood test for tumor DNA
D) A needle aspiration of fluid
  • 15. What do liquid biopsies analyze to track tumor progression?
A) Biopsy of bone marrow
B) Circulating tumor cells and cell-free DNA
C) Tissue density in the liver
D) X-ray images of the lungs
  • 16. Which artery is frequently biopsied when vasculitis is suspected?
A) Radial artery
B) Carotid artery
C) Femoral artery
D) Temporal artery
  • 17. What is vital in the diagnosis of Crescentic glomerulonephritis?
A) MRI imaging
B) Blood glucose testing
C) Genetic sequencing
D) Immunofluorescence
  • 18. Which condition involves the accumulation of degraded proteins in body tissues?
A) Vasculitis
B) Glomerulonephritis
C) Crohn's disease
D) Amyloidosis
  • 19. Where is a biopsy commonly taken to diagnose amyloidosis?
A) Heart
B) Liver
C) Gingiva
D) Brain
  • 20. Who specializes in diagnosing diseases by examining tissue under a microscope?
A) Radiologist
B) Pathologist
C) General practitioner
D) Surgeon
  • 21. What is done to the biopsy sample at the pathology laboratory to make individual cells more visible?
A) Dissolved in acid
B) Exposed to radiation
C) Frozen at extreme temperatures
D) Stained with dyes
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