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Promoter (genetics) - Quiz
Contributed by: Woolley
  • 1. What is the primary function of a promoter in genetics?
A) To terminate the process of DNA replication
B) To encode the primary structure of amino acids
C) To initiate the transcription of a single RNA transcript
D) To store genetic information for long-term inheritance
  • 2. Where are promoters typically located in relation to a gene?
A) Within the ribosomal subunits
B) Downstream on the antisense strand
C) Upstream on the DNA
D) Inside the protein coding region
  • 3. What enzyme is responsible for synthesizing RNA by binding to the promoter?
A) DNA polymerase
B) Ligase
C) RNA polymerase
D) Helicase
  • 4. What is the approximate length range of a promoter?
A) 1–10 base pairs
B) 10–50 base pairs
C) 100–1000 base pairs
D) 5000–10000 base pairs
  • 5. Which proteins bind to promoters to recruit RNA polymerase?
A) Transcription factors
B) Sigma factors only
C) Ribosomes
D) DNA helicases
  • 6. What factor is associated with RNA polymerase in bacteria for promoter recognition?
A) TBP
B) Sigma factor
C) TFB
D) RNA polymerase II
  • 7. How many different factors are at least required for RNA polymerase II to bind to a eukaryotic promoter?
A) Three
B) Only one
C) Fifty
D) At least seven
  • 8. Which elements are contained within archaeal promoters?
A) Sigma factors
B) Only enhancers
C) Only silencers
D) BRE and TATA elements
  • 9. What proteins recognize the BRE and TATA elements in archaea?
A) Sigma factor
B) TFB and TBP
C) RNA polymerase II
D) Enhancer binding proteins
  • 10. Besides promoters, what other regulatory regions can direct transcription?
A) Introns and exons
B) Ribosomes and tRNAs
C) Enhancers, silencers, and insulators
D) Only termination sequences
  • 11. What percentage of random sequences in E. coli can serve as active promoters without evolution?
A) Almost 100%
B) Less than 1%
C) About 10%
D) About 60%
  • 12. What percentage of random sequences in E. coli can evolve levels comparable to the lac promoter with one mutation?
A) About 5%
B) About 60%
C) About 90%
D) About 10%
  • 13. What determines the sequence of a promoter?
A) The number of ribosomes in the cell
B) The gene, transcription product, RNA polymerase type, and species
C) The age of the organism
D) The size of the cell nucleus
  • 14. What type of molecules can be produced via transcription initiated by a promoter?
A) Only DNA strands
B) Only proteins
C) Only lipids
D) mRNA, tRNA, or rRNA
  • 15. What causes a promoter to be induced?
A) The removal of DNA
B) Changes in temperature only
C) The binding of DNA polymerase
D) Changes in abundance or conformation of regulatory proteins
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