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Supercritical Fluid Chromatography - Quiz
Contributed by: Porter
  • 1. Which of the following is commonly used as the mobile phase in SFC?
A) Acetone
B) Water
C) Carbon dioxide
D) Methanol
  • 2. What state is the mobile phase in SFC?
A) Liquid
B) Gas
C) Supercritical
D) Solid
  • 3. What is the mechanism of separation in SFC based on?
A) Differences in molecular weight
B) Differences in boiling point
C) Differences in solubility in the mobile phase
D) Differences in conductivity
  • 4. What is the purpose of using a back pressure regulator in SFC?
A) Enhance detector sensitivity
B) Maintain supercritical conditions
C) Avoid solvent contamination
D) Increase column temperature
  • 5. What advantage does SFC offer over traditional HPLC?
A) Lower equipment cost
B) Limited application range
C) Faster separation
D) Higher resolution
  • 6. What role does co-solvent play in SFC separations?
A) Improves stationary phase selectivity
B) Enhances analyte solubility
C) Reduces detector interference
D) Stabilizes column efficiency
  • 7. Which term describes the region where the mobile phase in SFC exhibits properties of both a liquid and a gas?
A) Transition zone
B) Near-critical region
C) Critical point
D) Supercritical zone
  • 8. At supercritical conditions, the density of carbon dioxide is similar to that of which phase?
A) Solid
B) Gas
C) Aqueous
D) Liquid
  • 9. How can the properties of a supercritical fluid be adjusted?
A) Through exposure to light.
B) By changing the pressure and temperature, allowing fine-tuning between liquid-like and gas-like states.
C) By adding impurities.
D) By altering its chemical composition.
  • 10. Under what condition can a binary mixture of supercritical fluids form two immiscible gas phases?
A) At low pressures regardless of temperature.
B) Only when both components have identical critical points.
C) In all binary mixtures without exception.
D) When one component is much more volatile than the other, at high pressure and temperatures above the component critical points.
  • 11. How can the critical point of a binary mixture be estimated?
A) As the arithmetic mean of the critical temperatures and pressures of the two components.
B) Using only the critical temperature of one component.
C) It cannot be estimated; it must always be measured experimentally.
D) By summing the critical points of each component.
  • 12. What methods can provide greater accuracy in calculating the critical point of a binary mixture?
A) Through direct measurement at all possible pressures and temperatures.
B) By averaging the boiling points of the components.
C) Using only empirical observations without calculations.
D) Equations of state, such as the Peng–Robinson or group-contribution methods.
  • 13. What separates the gas and liquid region in a pressure-temperature phase diagram?
A) The boiling curve
B) The critical point
C) The density-pressure line
D) The melting curve
  • 14. What is the critical pressure of carbon dioxide?
A) 40 bar
B) 3.4 MPa (34 bar)
C) 7.38 MPa (73.8 bar)
D) 570 MPa
  • 15. What happens to the density of a gas as it approaches the critical temperature?
A) The density fluctuates unpredictably
B) The density remains constant
C) The density becomes higher
D) The density decreases significantly
  • 16. What is the minimum pressure required to compress supercritical CO2 into a solid at certain temperatures?
A) 7.38 MPa (73.8 bar)
B) 570 MPa
C) 14,000 MPa
D) 3.4 MPa (34 bar)
  • 17. Who discovered the critical point of a substance in 1822?
A) Baron Charles Cagniard de la Tour
B) Benjamin Thompson
C) Michael Faraday
D) James Prescott Joule
  • 18. In which field has supercritical fluid been used to create decaffeinated coffee?
A) Pharmaceuticals
B) Microelectronics
C) Food science
D) Cosmetics
  • 19. What is the surface temperature of Venus in Kelvin?
A) 500 K
B) 735 K
C) 273 K
D) 300 K
  • 20. What is the surface pressure on Venus in megapascals?
A) 5.0 megapascals
B) 1.0 megapascal
C) 12.0 megapascals
D) 9.3 megapascals
  • 21. What type of equipment uses liquid CO2 instead of supercritical CO2 to avoid damage?
A) Biomass gasification reactors.
B) Supercritical fluid extraction equipment.
C) Hydrogen production facilities.
D) CO2-based dry cleaning equipment.
  • 22. What is one advantage of using supercritical fluids in chemical reactions?
A) They increase reaction time.
B) They are cheaper than conventional solvents.
C) They eliminate the need for catalysts.
D) Rapid diffusion accelerates diffusion-controlled reactions.
  • 23. What range of particle sizes can be achieved using supercritical fluids?
A) 50–500 nm
B) 100–10000 nm
C) 10–5000 µm
D) 5–2000 nm
  • 24. What is the primary benefit of using supercritical drying in manufacturing aerogels?
A) It enhances the mechanical strength of the aerogel.
B) It removes solvent without causing distortion due to surface tension.
C) It speeds up the drying process significantly.
D) It reduces the cost of materials used.
  • 25. Why does supercritical water electrolysis improve electrical efficiency?
A) It eliminates bubbles on electrodes, reducing ohmic losses.
B) It increases the volume of hydrogen produced.
C) It uses less energy to heat the water.
D) It decreases the need for catalysts.
  • 26. What happens to lignin during supercritical water hydrolysis?
A) Lignin remains unchanged due to short reaction times.
B) Lignin is completely converted into simple sugars.
C) Aliphatic inter-ring linkages are cleaved into low molecular weight mixed phenols.
D) Lignin forms a protective layer around polysaccharides.
  • 27. What is a necessary condition for effective supercritical water hydrolysis?
A) Large amounts of water are needed to maintain the reaction.
B) Supercritical conditions can only be achieved at low pressures.
C) A continuous reaction system must be devised due to very short reaction times.
D) The process requires long reaction times to be effective.
  • 28. What gases are primarily produced during supercritical water gasification?
A) O2, N2, Ar
B) H2, CH4, CO2, CO
C) NH3, SO2, NOx
D) Neon, Krypton, Xenon
  • 29. What reaction converts vegetable oil into biodiesel?
A) Hydrogenation
B) Transesterification
C) Oxidation
D) Fermentation
  • 30. What is one proposed application of supercritical carbon dioxide in power generation?
A) Otto cycle
B) Brayton cycle
C) The Allam cycle
D) Rankine cycle
  • 31. What is the main advantage of using supercritical water reactors (SCWRs)?
A) Lower operational costs.
B) Reduced radiation exposure.
C) Increased fuel availability.
D) Similar thermal efficiency gains.
  • 32. Which natural gas field is known for isolating fossil CO2 and using carbon storage?
A) Texas gas field
B) Sleipner gas field
C) North Sea gas field
D) Alaska gas field
  • 33. Which country has marketed high-temperature domestic water heat pumps using supercritical carbon dioxide?
A) Japan
B) India
C) South Korea
D) China
  • 34. What property does CO2 exhibit at high pressures that is useful for various applications?
A) Reduced density
B) Enhanced conductivity
C) Increased viscosity
D) Antimicrobial properties
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