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Supercritical Fluid Chromatography - Quiz
Contributed by: Porter
  • 1. Which of the following is commonly used as the mobile phase in SFC?
A) Carbon dioxide
B) Water
C) Methanol
D) Acetone
  • 2. What state is the mobile phase in SFC?
A) Gas
B) Solid
C) Supercritical
D) Liquid
  • 3. What is the mechanism of separation in SFC based on?
A) Differences in boiling point
B) Differences in molecular weight
C) Differences in solubility in the mobile phase
D) Differences in conductivity
  • 4. What is the purpose of using a back pressure regulator in SFC?
A) Avoid solvent contamination
B) Increase column temperature
C) Enhance detector sensitivity
D) Maintain supercritical conditions
  • 5. What advantage does SFC offer over traditional HPLC?
A) Faster separation
B) Lower equipment cost
C) Higher resolution
D) Limited application range
  • 6. What role does co-solvent play in SFC separations?
A) Stabilizes column efficiency
B) Reduces detector interference
C) Enhances analyte solubility
D) Improves stationary phase selectivity
  • 7. Which term describes the region where the mobile phase in SFC exhibits properties of both a liquid and a gas?
A) Critical point
B) Near-critical region
C) Supercritical zone
D) Transition zone
  • 8. At supercritical conditions, the density of carbon dioxide is similar to that of which phase?
A) Aqueous
B) Liquid
C) Gas
D) Solid
  • 9. How can the properties of a supercritical fluid be adjusted?
A) Through exposure to light.
B) By altering its chemical composition.
C) By adding impurities.
D) By changing the pressure and temperature, allowing fine-tuning between liquid-like and gas-like states.
  • 10. Under what condition can a binary mixture of supercritical fluids form two immiscible gas phases?
A) Only when both components have identical critical points.
B) At low pressures regardless of temperature.
C) In all binary mixtures without exception.
D) When one component is much more volatile than the other, at high pressure and temperatures above the component critical points.
  • 11. How can the critical point of a binary mixture be estimated?
A) It cannot be estimated; it must always be measured experimentally.
B) Using only the critical temperature of one component.
C) As the arithmetic mean of the critical temperatures and pressures of the two components.
D) By summing the critical points of each component.
  • 12. What methods can provide greater accuracy in calculating the critical point of a binary mixture?
A) By averaging the boiling points of the components.
B) Through direct measurement at all possible pressures and temperatures.
C) Equations of state, such as the Peng–Robinson or group-contribution methods.
D) Using only empirical observations without calculations.
  • 13. What separates the gas and liquid region in a pressure-temperature phase diagram?
A) The density-pressure line
B) The boiling curve
C) The critical point
D) The melting curve
  • 14. What is the critical pressure of carbon dioxide?
A) 3.4 MPa (34 bar)
B) 40 bar
C) 7.38 MPa (73.8 bar)
D) 570 MPa
  • 15. What happens to the density of a gas as it approaches the critical temperature?
A) The density remains constant
B) The density decreases significantly
C) The density becomes higher
D) The density fluctuates unpredictably
  • 16. What is the minimum pressure required to compress supercritical CO2 into a solid at certain temperatures?
A) 3.4 MPa (34 bar)
B) 7.38 MPa (73.8 bar)
C) 14,000 MPa
D) 570 MPa
  • 17. Who discovered the critical point of a substance in 1822?
A) James Prescott Joule
B) Michael Faraday
C) Benjamin Thompson
D) Baron Charles Cagniard de la Tour
  • 18. In which field has supercritical fluid been used to create decaffeinated coffee?
A) Food science
B) Pharmaceuticals
C) Microelectronics
D) Cosmetics
  • 19. What is the surface temperature of Venus in Kelvin?
A) 300 K
B) 500 K
C) 273 K
D) 735 K
  • 20. What is the surface pressure on Venus in megapascals?
A) 1.0 megapascal
B) 9.3 megapascals
C) 5.0 megapascals
D) 12.0 megapascals
  • 21. What type of equipment uses liquid CO2 instead of supercritical CO2 to avoid damage?
A) Hydrogen production facilities.
B) CO2-based dry cleaning equipment.
C) Biomass gasification reactors.
D) Supercritical fluid extraction equipment.
  • 22. What is one advantage of using supercritical fluids in chemical reactions?
A) They eliminate the need for catalysts.
B) They are cheaper than conventional solvents.
C) Rapid diffusion accelerates diffusion-controlled reactions.
D) They increase reaction time.
  • 23. What range of particle sizes can be achieved using supercritical fluids?
A) 5–2000 nm
B) 10–5000 µm
C) 100–10000 nm
D) 50–500 nm
  • 24. What is the primary benefit of using supercritical drying in manufacturing aerogels?
A) It enhances the mechanical strength of the aerogel.
B) It speeds up the drying process significantly.
C) It reduces the cost of materials used.
D) It removes solvent without causing distortion due to surface tension.
  • 25. Why does supercritical water electrolysis improve electrical efficiency?
A) It eliminates bubbles on electrodes, reducing ohmic losses.
B) It uses less energy to heat the water.
C) It decreases the need for catalysts.
D) It increases the volume of hydrogen produced.
  • 26. What happens to lignin during supercritical water hydrolysis?
A) Lignin is completely converted into simple sugars.
B) Lignin forms a protective layer around polysaccharides.
C) Aliphatic inter-ring linkages are cleaved into low molecular weight mixed phenols.
D) Lignin remains unchanged due to short reaction times.
  • 27. What is a necessary condition for effective supercritical water hydrolysis?
A) The process requires long reaction times to be effective.
B) Large amounts of water are needed to maintain the reaction.
C) Supercritical conditions can only be achieved at low pressures.
D) A continuous reaction system must be devised due to very short reaction times.
  • 28. What gases are primarily produced during supercritical water gasification?
A) H2, CH4, CO2, CO
B) Neon, Krypton, Xenon
C) O2, N2, Ar
D) NH3, SO2, NOx
  • 29. What reaction converts vegetable oil into biodiesel?
A) Oxidation
B) Hydrogenation
C) Transesterification
D) Fermentation
  • 30. What is one proposed application of supercritical carbon dioxide in power generation?
A) The Allam cycle
B) Rankine cycle
C) Brayton cycle
D) Otto cycle
  • 31. What is the main advantage of using supercritical water reactors (SCWRs)?
A) Reduced radiation exposure.
B) Lower operational costs.
C) Increased fuel availability.
D) Similar thermal efficiency gains.
  • 32. Which natural gas field is known for isolating fossil CO2 and using carbon storage?
A) Texas gas field
B) Alaska gas field
C) Sleipner gas field
D) North Sea gas field
  • 33. Which country has marketed high-temperature domestic water heat pumps using supercritical carbon dioxide?
A) Japan
B) China
C) South Korea
D) India
  • 34. What property does CO2 exhibit at high pressures that is useful for various applications?
A) Enhanced conductivity
B) Increased viscosity
C) Reduced density
D) Antimicrobial properties
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