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Parkinson-plus syndrome - Quiz
Contributed by: Austin
  • 1. What distinguishes Parkinson-plus syndromes from idiopathic Parkinson's disease?
A) Complete lack of tremor
B) Age of onset exclusively under 30
C) Additional clinical features
D) Inability to walk
  • 2. Which of the following is considered a Parkinson-plus syndrome?
A) Huntington's disease
B) Multiple sclerosis
C) Progressive supranuclear palsy
D) Amyotrophic lateral sclerosis
  • 3. How are Parkinson-plus syndromes classified based on pathology?
A) Primary and secondary
B) Synucleinopathies and tauopathies
C) Acute and chronic
D) Genetic and metabolic
  • 4. What is another name for the autonomic failure seen in multiple system atrophy?
A) Corticobasal degeneration
B) Shy–Drager syndrome
C) Pick's disease
D) Supranuclear gaze palsy
  • 5. Which of the following is a clinical feature distinguishing PPS from idiopathic PD?
A) Late-onset postural instability
B) Excellent response to levodopa
C) Unilateral tremor
D) Symmetrical onset
  • 6. What diagnostic tool uses 123I-iodobenzamide to assist in the differential diagnosis of PPS?
A) MRI
B) SPECT
C) CT scan
D) PET scan
  • 7. Which disorder is recognized as the second-most common type of neurodegenerative dementia?
A) Progressive supranuclear palsy
B) Pick's disease
C) Corticobasal degeneration
D) Dementia with Lewy bodies
  • 8. Olivopontocerebellar atrophy is characterized by which symptoms?
A) Memory loss and hallucinations
B) Ataxia and dysarthria
C) Alien limb and apraxia
D) Resting tremor and rigidity
  • 9. How do Parkinson-plus syndromes generally respond to antiparkinsonian medication compared to PD?
A) They respond significantly better
B) They are less likely to respond
C) They show identical response
D) They react negatively to all medication
  • 10. What is the primary approach to therapy for Parkinson-plus syndromes?
A) Preventative gene therapy
B) Curative surgery
C) Multidisciplinary treatment of symptoms
D) High-dose levodopa monotherapy
  • 11. Which of these is a recognized motor feature of Parkinson-plus syndromes?
A) Spontaneous recovery
B) Supranuclear gaze palsy
C) Increased dopamine production
D) Reduced axial muscle rigidity
  • 12. What is the nature of the progression of Parkinson-plus syndromes compared to PD?
A) More slowly progressive
B) More rapidly progressive
C) Stable without progression
D) Reversible
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