- 1. Clinical immunology is the branch of medicine that focuses on diagnosing and treating disorders related to the immune system. This field encompasses a wide range of conditions, including allergies, autoimmune diseases, immunodeficiencies, and transplant rejection. Clinical immunologists work closely with patients to understand the underlying causes of their immune-related health issues and develop personalized treatment plans. They may utilize a variety of techniques, such as blood tests, imaging studies, and immunotherapy, to help manage and alleviate symptoms. By studying the body's immune responses, clinical immunologists play a crucial role in improving patient outcomes and enhancing overall quality of life.
What is the main function of T cells in immunology?
A) Producing antibodies
B) Secreting cytokines
C) Phagocytosis
D) Regulating immune responses
- 2. Which type of immunity is acquired through vaccination?
A) Innate immunity
B) Cell-mediated immunity
C) Passive immunity
D) Adaptive immunity
- 3. Which cells are responsible for antibody production?
A) Macrophages
B) B cells
C) T cells
D) NK cells
- 4. Which immunoglobulin is the most abundant in serum?
A) IgA
B) IgE
C) IgM
D) IgG
- 5. Which type of hypersensitivity reaction involves IgE antibodies?
A) Type II
B) Type III
C) Type IV
D) Type I
- 6. Which cells express major histocompatibility complex (MHC) class II molecules?
A) Neutrophils
B) Antigen-presenting cells
C) Cytotoxic T cells
D) NK cells
- 7. Where do B cells mature and differentiate?
A) Lymph nodes
B) Spleen
C) Bone marrow
D) Thymus
- 8. What is the purpose of the major histocompatibility complex (MHC) in the immune system?
A) Regulating inflammation
B) Directly killing pathogens
C) Producing antibodies
D) Presenting antigens to T cells
- 9. Which type of hypersensitivity reaction involves immune complex formation?
A) Type I
B) Type IV
C) Type II
D) Type III
- 10. What is the function of regulatory T cells?
A) Activating B cells
B) Producing antibodies
C) Suppressing immune responses
D) Killing infected cells
- 11. Which molecule is targeted by monoclonal antibody therapies in autoimmune diseases?
A) MHC molecules
B) Immunoglobulins
C) Complement proteins
D) Cytokines
- 12. Which cells secrete antibodies in response to antigens?
A) Mast cells
B) T cells
C) Memory B cells
D) Plasma cells
- 13. Which cells are responsible for immune surveillance against cancer cells?
A) Regulatory T cells
B) Natural killer cells
C) Dendritic cells
D) Macrophages
- 14. Where do T cells mature?
A) Spleen
B) Thymus
C) Bone marrow
D) Lymph nodes
- 15. Which immunodeficiency disorder is caused by a genetic defect in B cells?
A) DiGeorge syndrome
B) SCID
C) Ataxia-telangiectasia
D) X-linked agammaglobulinemia
- 16. Which cytokine promotes the differentiation of B cells into plasma cells?
A) IL-2
B) TNF-alpha
C) IFN-gamma
D) IL-6
- 17. Which type of immunodeficiency disorder is characterized by low levels of immunoglobulins in the blood?
A) Ataxia-telangiectasia
B) Hypogammaglobulinemia
C) CVID
D) DiGeorge syndrome
- 18. Which antibody is involved in defense against parasites?
A) IgG
B) IgM
C) IgA
D) IgE
- 19. Which cytokine is responsible for promoting growth and differentiation of B cells?
A) Interleukin-4
B) Tumor necrosis factor
C) Interleukin-10
D) Interferon-gamma
- 20. Which immunoglobulin plays a role in mucosal immunity and provides passive immunity to infants through breast milk?
A) IgD
B) IgM
C) IgA
D) IgE
- 21. What is the primary function of toll-like receptors in the innate immune response?
A) Regulate inflammation
B) Recognize pathogen-associated molecular patterns
C) Activate complement system
D) Induce antibody production
- 22. Which of the following is not a major histocompatibility complex (MHC) class II molecule?
A) HLA-DP
B) CD8
C) HLA-DR
D) HLA-DQ
- 23. What is the hallmark of a secondary immune response compared to a primary immune response?
A) Decreased antibody production
B) Fewer memory cells generated
C) Faster and more robust response
D) Higher antigen dose required for response
- 24. Which pattern recognition receptor is responsible for recognizing bacterial cell wall components such as lipopolysaccharide?
A) TLR4
B) TLR9
C) RIG-I
D) NOD2
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